Abstract Encapsulation in polymer NPs (NPs) is a well-recognized way to improve the oral
bioavailability of hydrophobic and hydrophilic compounds by enhancing their solubility in …

Oral administration is the preferred route of drug delivery in clinical practice due to its
noninvasiveness, safety, convenience, and high patient compliance. The gastrointestinal …

Diabetes mellitus is a metabolic endocrine disease characterized by chronic hyperglycemia
with disturbances in metabolic processes, such as those related to carbohydrates, fat, and …

In drug discovery and drug development, it is estimated that around 40% of commercialized
and 90% of under-study drugs have inadequate pharmaceutical properties, severely …

Mucoadhesive polymers represent a major part of site-specific and localized retention
strategies in oral drug delivery. The present research was designed to synthesize and …

Abstract Gold nanoparticles (AuNPs)-mediated Photothermal Therapy (PTT) is a minimally-
invasive therapeutic approach that uses AuNPs to convert light into heat, leading to the …

Diabetes mellitus (DM) prevalence is rising worldwide. Current therapies comprising
subcutaneous insulin injections can cause adverse effects such as lipodystrophy, local …

The lipophilicity of a peptide drug can be considerably increased by hydrophobic ion pairing
with amphiphilic counterions for successful incorporation into lipid-based formulations …

Insulin is a peptide hormone with many physiological functions, besides its use in diabetes
treatment. An important role of insulin is related to the wound healing process—however …

Insulin, a pivotal anabolic hormone, regulates glucose homeostasis by facilitating the
conversion of blood glucose to energy or storage. Dysfunction in insulin activity, often …