Nanotechnology-based antiviral therapeutics

M Chakravarty, A Vora - Drug Delivery and Translational Research, 2021 - Springer
The host immune system is highly compromised in case of viral infections and relapses are
very common. The capacity of the virus to destroy the host cell by liberating its own DNA or …

Dengue, chikungunya, and Zika virus infections in Latin America and the Caribbean: a systematic review

LLM Santos, EC de Aquino… - … de Salud Pública, 2023 - SciELO Public Health
Objectives. To characterize the distribution profile of dengue, chikungunya, and Zika virus
infections in Latin America and the Caribbean and to identify possible factors associated …

Social determinants of mortality from COVID-19: A simulation study using NHANES

B Seligman, M Ferranna, DE Bloom - PLoS medicine, 2021 - journals.plos.org
Background The COVID-19 epidemic in the United States is widespread, with more than
200,000 deaths reported as of September 23, 2020. While ecological studies show higher …

A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses

NA Prow, L Liu, E Nakayama, TH Cooper, K Yan… - Nature …, 2018 - nature.com
Zika and chikungunya viruses have caused major epidemics and are transmitted by Aedes
aegypti and/or Aedes albopictu s mosquitoes. The “Sementis Copenhagen Vector”(SCV) …

Reemergence of yellow fever virus in southeastern Brazil, 2017–2018: What sparked the spread?

JI Rosser, K Nielsen-Saines, E Saad… - PLoS neglected tropical …, 2022 - journals.plos.org
Background The 2017–2018 yellow fever virus (YFV) outbreak in southeastern Brazil
marked a reemergence of YFV in urban states that had been YFV-free for nearly a century …

Space–time dynamics of a triple epidemic: dengue, chikungunya and Zika clusters in the city of Rio de Janeiro

LP Freitas, OG Cruz, R Lowe… - Proceedings of the …, 2019 - royalsocietypublishing.org
Dengue, an arboviral disease transmitted by Aedes mosquitoes, has been endemic in Brazil
for decades. However, vector-control strategies have not led to a significant reduction in the …

Zika virus vertical transmission in children with confirmed antenatal exposure

P Brasil, Z Vasconcelos, T Kerin, CR Gabaglia… - Nature …, 2020 - nature.com
We report Zika virus (ZIKV) vertical transmission in 130 infants born to PCR+ mothers at the
time of the Rio de Janeiro epidemic of 2015–2016. Serum and urine collected from birth …

Insecticide resistance and genetic structure of Aedes aegypti populations from Rio de Janeiro State, Brazil

RU Rahman, LV Cosme, MM Costa… - PLoS neglected …, 2021 - journals.plos.org
Vector control largely relies on neurotoxic chemicals, and insecticide resistance (IR) directly
threatens their effectiveness. In some cases, specific alleles cause IR, and knowledge of the …

Circulation of chikungunya virus East/Central/South African lineage in Rio de Janeiro, Brazil

J Xavier, M Giovanetti, V Fonseca, J Thézé, T Gräf… - PloS one, 2019 - journals.plos.org
The emergence of chikungunya virus (CHIKV) has raised serious concerns due to the virus'
rapid dissemination into new geographic areas and the clinical features associated with …

Retrospective genomic surveillance of Chikungunya transmission in minas gerais state, southeast Brazil

H Fritsch, M Giovanetti, J Xavier… - Microbiology …, 2022 - Am Soc Microbiol
Brazil accounted for a total number of 1,276,194 reported cases of chikungunya fever
between 2014 and 2022. Additionally, since 2015, the country has experienced an …