Perfusion is a fundamental biological function that refers to the delivery of oxygen and
nutrients to tissue by means of blood flow. Perfusion MRI is sensitive to microvasculature …

The non-invasive nature of arterial spin labelling (ASL) has opened a unique window into
human brain function and perfusion physiology. High spatial and temporal resolution makes …

The two most common methods for measuring perfusion with MRI are based on dynamic
susceptibility contrast (DSC) and arterial spin labeling (ASL). Although clinical experience to …

Arterial spin labeling (ASL) perfusion imaging provides direct and absolute measurement of
cerebral blood flow (CBF). Arterial transit time is a related physiological parameter reflecting …

Arterial spin labeling is a magnetic resonance method for the measurement of cerebral
blood flow. In its simplest form, the perfusion contrast in the images gathered by this …

Normal aging is associated with diminished brain perfusion measured as cerebral blood
flow (CBF), but previously it is difficult to accurately measure various aspects of perfusion …

A two‐compartment exchange model for perfusion quantification using arterial spin labeling
(ASL) is presented, which corrects for the assumption that the capillary wall has infinite …

Cerebral metabolic rate of oxygen (CMRO2) is an important marker for brain function and
brain health. Existing techniques for quantification of CMRO2 with positron emission …

Caffeine is a commonly used neurostimulant that also produces cerebral vasoconstriction by
antagonizing adenosine receptors. Chronic caffeine use results in an adaptation of the …

The three-dimensional spatial arrangement of the cortical microcirculatory system is critical
for understanding oxygen exchange between blood vessels and brain cells. A three …