The analogy of mitochondria as powerhouses has expired. Mitochondria are living, dynamic,
maternally inherited, energy-transforming, biosynthetic, and signaling organelles that …

The clinical development of selective alpha-7 nicotinic acetylcholine receptor (α7 nAChR)
agonists has hitherto been focused on disorders characterized by cognitive deficits (eg …

Mitochondria are multifunctional and dynamic organelles deeply integrated into cellular
physiology and metabolism. Disturbances in mitochondrial function are involved in several …

The neurotransmitter acetylcholine (ACh) acts as an autocrine growth factor for human lung
cancer. Several lines of evidence show that lung cancer cells express all of the proteins …

Pemphigus vulgaris (PV) is a potentially life-threatening mucocutaneous autoimmune
blistering disease. Patients develop non-healing erosions and blisters due to cell–cell …

Severe socioeconomic deprivation (SED) and adverse childhood experiences (ACE) are
significantly associated with the development in adulthood of (i) enhanced inflammatory …

The α7 nicotinic acetylcholine receptor (α7 nAChR) is highly expressed in the brain, where it
maintains various neuronal functions including (but not limited to) learning and memory. In …

Nicotinic acetylcholine receptors (nAChRs) have long been considered to solely mediate
neurotransmission. However, their widespread distribution in the human body suggests a …

Critical illnesses and injuries are recognized as major threats to human health, and they are
usually accompanied by uncontrolled inflammation and dysfunction of immune response …

Nicotinic acetylcholine receptors (nAChR) are widely distributed in neuronal and non-
neuronal tissues, where they play diverse physiological roles. In this review, we highlight the …