Simple Summary Reprogramming of glucose metabolism is a hallmark of cancer and can be
targeted by therapeutic agents. Some metabolism regulators, such as ivosidenib and …

Hypoxic environment is an important feature of solid tumors, which comes from the
imbalance of oxygen supply and consumption. Over the past few years, substantial progress …

As human life expectancy is rising, the incidence of age-associated diseases will also
increase. Scientific evidence has revealed that healthy diets, including good fats, vitamins …

Mitochondrial diseases (MDs) may result from mutations affecting nuclear or mitochondrial
genes, encoding mitochondrial proteins, or non-protein-coding mitochondrial RNA. Despite …

Ferroptosis, a recently identified form of regulated cell death characterized by the iron-
dependent accumulation of lethal lipid peroxidation, has gained increasing attention in …

Abstract Vitamin K1 (VitK1) and Vitamin K2 (VitK2), two important naturally occurring
micronutrients in the VitK family, found, respectively, in green leafy plants and algae (VitK1) …

Abstract Background: Menaquinone-4 (MK-4), the isoform of vitamin K2 in the brain, exerts
neuroprotective effects against a variety of central nervous system disorders. This study …

Ferroptosis is a recently discovered form of programmed cell death. It is characterized by the
accumulation of iron and lipid hydroperoxides in cells. Vitamin K is known to have …

Abstract Oral Squamous Cell Carcinoma (OSCC) is the sixth most common cancer
worldwide. Chemoresistance is a critical problem in OSCC leading to therapeutic failure and …

Cellular redox status has been considered as a focal point for the pathogenesis of multiple
disorders. High and persistent levels of free radicals kick off inflammation and associated …