Bone morphogenetic proteins: facts, challenges, and future perspectives

AC Carreira, FH Lojudice, E Halcsik… - Journal of dental …, 2014 - journals.sagepub.com
Bone morphogenetic proteins (BMPs) are members of the TGF-β superfamily, acting as
potent regulators during embryogenesis and bone and cartilage formation and repair. Cell …

Advancements in carboxymethyl cellulose (CMC) modifications and their diverse biomedical applications: a comprehensive review

RR Kurhade, MS Shaikh, V Nagulwar… - International Journal of …, 2024 - Taylor & Francis
A Comprehensive Review delves into the evolution of carboxymethyl cellulose (CMC)
modifications and their extensive utilization in biomedical fields. Various cross-linking …

Islet transplantation: overcoming the organ shortage

MC Mantovani, I Gabanyi, CA Pantanali… - Diabetology & Metabolic …, 2023 - Springer
Background Type 1 diabetes mellitus (T1D) is a condition resulting from autoimmune
destruction of pancreatic β cells, leading patients to require lifelong insulin therapy, which …

A fusion between domains of the human bone morphogenetic protein-2 and maize 27 kD γ-zein accumulates to high levels in the endoplasmic reticulum without …

V Ceresoli, D Mainieri, M Del Fabbro… - Frontiers in Plant …, 2016 - frontiersin.org
Human Bone Morphogenetic Protein-2 (hBMP2) is an osteoinductive agent physiologically
involved in bone remodeling processes. A commercialized recombinant hBMP2 produced in …

Advanced therapy medicinal products in type I diabetes mellitus: technological and regulatory challenges

C Leal-Lopes, MC Mantovani… - … Sanitaria Em Debate …, 2018 - observatorio.fm.usp.br
O diabetes mellitus do tipo 1 (T1DM) é uma desordem autoimune que culmina na
destruição das células β-pancreáticas produtoras de insulina. Atualmente, Produtos …

In vitro differentiation of cGMP-grade retinal pigmented epithelium from human embryonic stem cells

FH Lojudice, RAB Fernandes, F Innocenti… - International Journal of …, 2019 - Springer
Abstract Background The World Health Organization (WHO) estimates that the number of
individuals who lose their vision due to retinal degeneration is expected to reach 6 million …

Cytotoxic mechanisms of islet amyloid polypeptide in the pathogenesis of type-2 diabetes mellitus (T2DM)

TL Degaki, DHJ Lopes, MC Sogayar - Non-fibrillar Amyloidogenic Protein …, 2012 - Springer
Diabetes mellitus (DM) is a chronic syndrome that occurs due to loss of the insulin-
producing β-cells in the islets of Langerhans of the pancreas by a β-cell-specific …

Production of Human Recombinant Differentiation Factors in Transgenic Tobacco Plants

V Ceresoli - 2015 - air.unimi.it
Research on bone regeneration began decades ago as a result of intensive studies on bone
growth and healing. Bone has been recognised, among the many tissues in human body, as …

[引用][C] 高效能沉默BMP-7 基因siRNA 序列的实验筛选

李彩霞, 白鹏, 赵娴, 董苑, 代晓明, 李逸松, 刘流 - 南方医科大学学报, 2015