Magnetic field effects in biology from the perspective of the radical pair mechanism

H Zadeh-Haghighi, C Simon - Journal of the Royal …, 2022 - royalsocietypublishing.org
Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …

The circadian clock as a potential biomarker and therapeutic target in pancreatic cancer

G Pourali, AM Ahmadzade, M Arastonejad… - Molecular and cellular …, 2024 - Springer
Pancreatic cancer (PC) has a very high mortality rate globally. Despite ongoing efforts, its
prognosis has not improved significantly over the last two decades. Thus, further …

Circadian regulator BMAL1:: CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle

M Qu, G Zhang, H Qu, A Vu, R Wu… - Proceedings of the …, 2023 - National Acad Sciences
Hepatocellular carcinoma (HCC) remains a global health challenge whose incidence is
growing worldwide. Previous evidence strongly supported the notion that the circadian clock …

ROR activation by Nobiletin enhances antitumor efficacy via suppression of IκB/NF-κB signaling in triple-negative breast cancer

E Kim, YJ Kim, Z Ji, JM Kang, M Wirianto… - Cell death & …, 2022 - nature.com
Triple-negative breast cancer (TNBC) is a heterogeneous disease characterized by poor
response to standard therapies and therefore unfavorable clinical outcomes. Better …

Integrated multi-omics analysis reveals the molecular interplay between circadian clocks and cancer pathogenesis

A Pérez-Villa, G Echeverría-Garcés… - Scientific Reports, 2023 - nature.com
Circadian rhythms (CRs) are fundamental biological processes that significantly impact
human well-being. Disruption of these rhythms can trigger insufficient neurocognitive …

Obesity, cancer risk, and time-restricted eating

M Das, NJG Webster - Cancer and Metastasis Reviews, 2022 - Springer
Obesity and the associated metabolic syndrome is considered a pandemic whose
prevalence is steadily increasing in many countries worldwide. It is a complex, dynamic, and …

Learning from circadian rhythm to transform cancer prevention, prognosis, and survivorship care

X Zhu, G Maier, S Panda - Trends in Cancer, 2024 - cell.com
Circadian timekeeping mechanisms and cell cycle regulation share thematic biological
principles in responding to signals, repairing cellular damage, coordinating metabolism, and …

It's about time: the circadian network as time-keeper for cognitive functioning, locomotor activity and mental health

M Yalçin, A Mundorf, F Thiel… - Frontiers in …, 2022 - frontiersin.org
A variety of organisms including mammals have evolved a 24h, self-sustained timekeeping
machinery known as the circadian clock (biological clock), which enables to anticipate …

[HTML][HTML] Interactions of circadian clock genes with the hallmarks of cancer

SM Ortega-Campos, EM Verdugo-Sivianes… - … et Biophysica Acta (BBA …, 2023 - Elsevier
The molecular machinery of the circadian clock regulates the expression of many genes and
processes in the organism, allowing the adaptation of cellular activities to the daily light-dark …

Evaluation and management of sleep and circadian rhythm disturbance in cancer

DD Balachandran, MA Miller, SA Faiz… - … treatment options in …, 2021 - Springer
Opinion statement Sleep and circadian rhythm disturbance are among the most commonly
experienced symptoms in patients with cancer. These disturbances occur throughout the …