Matrix metalloproteinases in normal pregnancy and preeclampsia

J Chen, RA Khalil - Progress in molecular biology and translational …, 2017 - Elsevier
Normal pregnancy is associated with marked hemodynamic and uterine changes that allow
adequate uteroplacental blood flow and uterine expansion for the growing fetus. These …

New insights into the role of matrix metalloproteinases in preeclampsia

S Espino Y Sosa, A Flores-Pliego… - International Journal of …, 2017 - mdpi.com
Preeclampsia is a severe pregnancy complication globally, characterized by poor
placentation triggering vascular dysfunction. Matrix metalloproteinases (MMPs) exhibit …

Mechanisms of endothelial dysfunction in hypertensive pregnancy and preeclampsia

JS Possomato-Vieira, RA Khalil - Advances in pharmacology, 2016 - Elsevier
Preeclampsia is a pregnancy-related disorder characterized by hypertension and could lead
to maternal and fetal morbidity and mortality. Although the causative factors and …

Association of endothelial nitric oxide synthase 894G> T polymorphism with preeclampsia risk: a systematic review and meta-analysis based on 35 studies

H Abbasi, SA Dastgheib, A Hadadan… - Fetal and pediatric …, 2021 - Taylor & Francis
Background Several case–control studies have been performed to investigate the
association between 894 G> T polymorphism in endothelial nitric oxide synthase (eNOS) …

Genetic variants in preeclampsia: Lessons from studies in Latin-American populations

RT Michita, VL Kaminski, JAB Chies - Frontiers in Physiology, 2018 - frontiersin.org
Placental vascularization is a tightly regulated physiological process in which the maternal
immune system plays a fundamental role. Vascularization of the maternal-placental interface …

Vascular dysfunction in mother and offspring during preeclampsia: contributions from Latin-American countries

FR Giachini, C Galaviz-Hernandez… - Current hypertension …, 2017 - Springer
Pregnancy is a physiologically stressful condition that generates a series of functional
adaptations by the cardiovascular system. The impact of pregnancy on this system persists …

Preeclampsia: inflammatory signature of decidual cells in early manifestation of disease

P Vishnyakova, A Poltavets, M Nikitina, K Muminova… - Placenta, 2021 - Elsevier
Introduction Preeclampsia is a pregnancy-specific complication characterized by
hypertension in combination with proteinuria and/or various manifestations of multiple organ …

The eNOS-G894T genetic polymorphism and risk of preeclampsia: A case-control study, an updated meta-analysis, and a bioinformatic assay

M Karimian, S Yaqubi, Z Karimian - Cytokine, 2023 - Elsevier
Objectives Preeclampsia (PE) is a leading cause of maternal death worldwide and involves
vascular endothelial dysfunction. The aim of this study was to investigate the association of …

[PDF][PDF] Polymorphisms in interleukin-6 and interleukin-10 may be associated with risk of preeclampsia

DM Fan, Y Wang, XL Liu, A Zhang, Q Xu - Genet Mol Res, 2017 - Citeseer
Preeclampsia is a common condition unique to pregnant women. Previous studies have
suggested that several cytokines may contribute to defective placental invasion and …

Association Between Endothelial Nitric Oxide Synthase (eNOS)− 786 T/C and 27-bp VNTR 4b/a Polymorphisms and Preeclampsia Development

T Sljivancanin Jakovljevic, O Kontic-Vucinic… - Reproductive …, 2021 - Springer
The aim of the present study was to analyze the distribution of genotypes and haplotypes of
functional eNOS gene polymorphisms in the promoter (− 786 T/C), intron 4 (VNTR4b/a) and …