Autoimmune hepatitis (AIH) is a rare disease of unclear etiology characterized by loss of self‐
tolerance that can lead to liver injury, cirrhosis, and acute liver failure. First‐line treatment …

Autoimmune hepatitis (AIH) is a rare disease of unclear etiology characterized by loss of self‐
tolerance that can lead to liver injury, cirrhosis, and acute liver failure. First‐line treatment …

Adoptive immunotherapy with Tregs is a promising approach for preventing or treating type
1 diabetes. Islet antigen–specific Tregs have more potent therapeutic effects than polyclonal …

Background T1D is an autoimmune disease in which pancreatic islets of Langerhans are
infiltrated by immune cells resulting in the specific destruction of insulin-producing islet beta …

The importance of regulatory T cells (Tregs) in preventing autoimmunity has been well
established; however, the precise alterations in Treg function in autoimmune individuals and …

Type 1 diabetes (T1D) results from the progressive destruction of pancreatic β-cells in a
process mediated primarily by T lymphocytes. The T1D research community has made …

Critical insights into the etiology of type 1 diabetes (T1D) came from genome-wide
association studies that unequivocally connected genetic susceptibility to immune cell …

Regulatory T cells (Tregs) are a promising candidate cell therapy to treat autoimmune
diseases and aid the longevity of transplanted solid organs. Despite increasing numbers of …

Regulatory T cells (Tregs) have become highly relevant in the pathophysiology and
treatment of autoimmune diseases, such as type 1 diabetes (T1D). As these cells are known …

Regulatory T cells (Tregs) are a subtype of CD4+ T cells that can mediate immune tolerance
by a multitude of immunomodulatory mechanisms. Treg-based adoptive immunotherapy is …