Simple Summary The high lethality of colorectal cancer (CRC) is anticipated to continue in
the following decades. Early-stage CRC is entirely treatable with surgery and adjuvant …

Colorectal cancer (CRC) is a leading cause of cancer death worldwide. It includes different
subtypes that differ in their clinical and prognostic features. In the past decade, in addition to …

Increasing evidence links the gut microbiota with colorectal cancer. Metagenomic analyses
indicate that symbiotic Fusobacterium spp. are associated with human colorectal carcinoma …

Chromosome segregation errors cause aneuploidy and genomic heterogeneity, which are
hallmarks of cancer in humans. A persistent high frequency of these errors (chromosomal …

Wnt signaling transduces evolutionarily conserved pathways which play important roles in
initiating and regulating a diverse range of cellular activities, including cell proliferation …

The strategy of using existing drugs originally developed for one disease to treat other
indications has found success across medical fields. Such drug repurposing promises faster …

The process by which normal cells become progressively transformed to malignancy is now
known to require the sequential acquisition of mutations which arise as a consequence of …

Purpose: Antitumor immune response changes drastically during the progression of
cancers. Established cancers often escape from the host immune system, although specific …

Objective: To update the authors' experience with intraductal papillary mucinous neoplasms
(IPMNs) of the pancreas. Background Data: IPMNs are intraductal mucin-producing cystic …

Colorectal cancer (CRC) incidence rates decreased by up to 50% in older age groups in the
USA in the era of the widespread uptake of screening colonoscopy, despite adverse trends …