Starch-binding domains as CBM families–history, occurrence, structure, function and evolution

Š Janeček, F Mareček, EA MacGregor… - Biotechnology Advances, 2019 - Elsevier
The term “starch-binding domain”(SBD) has been applied to a domain within an amylolytic
enzyme that gave the enzyme the ability to bind onto raw, ie thermally untreated, granular …

Microbial starch debranching enzymes: Developments and applications

W Xia, K Zhang, L Su, J Wu - Biotechnology Advances, 2021 - Elsevier
Starch debranching enzymes (SDBEs) hydrolyze the α-1, 6 glycosidic bonds in
polysaccharides such as starch, amylopectin, pullulan and glycogen. SDBEs are also …

Carbohydrate-binding modules facilitate the enzymatic hydrolysis of lignocellulosic biomass: Releasing reducing sugars and dissociative lignin available for …

Q Shi, AM Abdel-Hamid, Z Sun, Y Cheng, T Tu… - Biotechnology …, 2023 - Elsevier
The microbial decomposition and utilization of lignocellulosic biomass present in the plant
tissues are driven by a series of carbohydrate active enzymes (CAZymes) acting in concert …

Cyclodextrins: Only pharmaceutical excipients or full-fledged drug candidates?

T Kovacs, P Nagy, G Panyi, L Szente, Z Varga… - Pharmaceutics, 2022 - mdpi.com
Cyclodextrins, representing a versatile family of cyclic oligosaccharides, have extensive
pharmaceutical applications due to their unique truncated cone-shaped structure with a …

The binding mechanism between cyclodextrins and pullulanase: A molecular docking, isothermal titration calorimetry, circular dichroism and fluorescence study

X Li, Y Bai, H Ji, Z Jin - Food chemistry, 2020 - Elsevier
This work investigated the interaction between cyclodextrins and pullulanase to provide
insight into the production and application of cyclodextrins. Enzyme activity and kinetic …

Progress in cyclodextrins as important molecules regulating catalytic processes of glycoside hydrolases

X Li, Z Jin, Y Bai, B Svensson - Biotechnology Advances, 2024 - Elsevier
Cyclodextrins (CDs) are important starch derivatives and commonly comprise α-, β-, and γ-
CDs. Their hydrophilic surface and hydrophobic inner cavity enable regulation of enzyme …

Structure and substrate recognition by the Ruminococcus bromii amylosome pullulanases

DW Cockburn, R Kibler, HA Brown, R Duvall… - Journal of Structural …, 2021 - Elsevier
Pullulanases are glycoside hydrolase family 13 (GH13) enzymes that target α1, 6 glucosidic
linkages within starch and aid in the degradation of the α1, 4-and α1, 6-linked glucans …

Enzymatic Degradation of Starch—Usage of β‐Cyclodextrin for Inactivation of Pullulanase

M Ulbrich, M Bültena, E Flöter - Starch‐Stärke, 2024 - Wiley Online Library
The cyclic oligosaccharide β‐cyclodextrin (β‐CDx) is investigated regarding its ability on
principle to reduce the debranching activity of pullulanase (PUL) or even terminate the …

Direct Continuous Flow Synthesis of Two Difficult Polypeptides Using β-Cyclodextrins

S Szaniszló, G Schlosser, V Farkas… - The Journal of Organic …, 2024 - ACS Publications
This study focuses on investigating the use of β-cyclodextrin (β-CyD) derivatives as additives
in continuous flow peptide synthesis, with particular emphasis on challenging sequences …

Development of pullulanase mutants to enhance starch substrate utilization for efficient production of β-CD

X Li, H Ji, Y Bai, Z Jin - International Journal of Biological Macromolecules, 2021 - Elsevier
The inhibitory effect of β-CD on pullulanase which hydrolyzes α-1, 6 glycosidic bond in
starch to release more available linear substrates, limited substrate utilization thus …