Marek's disease (MD) in chickens was first described over a century ago and the causative
agent of this disease, Marek's disease virus (MDV), was first identified in the 1960's. There …

Marek's disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes deadly T-
cell lymphomas and serves as a natural virus-induced tumor model in chickens. Although …

Viral diseases pose major threats to humans and other animals, including the billions of
chickens that are an important food source as well as a public health concern due to …

Like mammals, the major histocompatibility complex (MHC) of chickens is the primary
genetic locus for graft rejection, and encodes polymorphic classical class I and class II …

Introduction: Our immune system discriminates self from non-self by examining the peptide
cargo of human leukocyte antigen (HLA) molecules displayed on the cell surface …

The functions of a wide variety of molecules with structures similar to the classical class I and
class II molecules encoded by the major histocompatibility complex (MHC) have been …

Simple Summary The poultry industry is the most intensive and fastest growing among all
livestock production systems, and, in the last decades, it has expanded exponentially due to …

It is more than a century since Marek's disease (MD) was first reported in chickens and since
then there have been concerted efforts to better understand this disease, its causative agent …

Reticuloendotheliosis virus (REV) is a retroviral pathogen capable of infecting several avian
hosts and is associated with immunosuppression, anemia, proventriculitis, neoplasia, and …

Abstract MHC class II (MHC-II) molecules play a crucial role in cellular and humoral
immunity by forming peptide–MHC-II (pMHC-II) complexes. The three-dimensional …