The trigeminal system is one of the most complex cranial nerve systems of the human body.
Research on it has vastly grown in recent years and concentrated more and more on …

Orofacial pain syndromes are common in clinical practice and tend to be unique in their
presentation owing to the complex anatomy and specialized sensory innervation of the face …

Somatosensation is topographically organized in the primary (S1) and secondary
somatosensory cortex (S2), which contributes to identify the region receiving sensory inputs …

This study examined the projections from the rat insular cortex (Ins) to lower brainstem areas
which are possibly involved in orofacial pain processing. We first examined distributions of …

Somatosensory information from the dental pulp is processed in the primary (S1) and
secondary somatosensory cortex (S2) and in the insular oral region (IOR). Stimulation of …

Neurons in the arm and orofacial regions of the sensorimotor cortex in behaving monkeys
display directional tuning of their activity during arm reaching and tongue protrusion …

The supratrigeminal nucleus (Su5) is a key structure for controlling jaw movements; it
receives proprioceptive sensation from jaw-closing muscle spindles (JCMSs) and sends …

Little is known about how proprioceptive signals arising from muscles reach to higher brain
regions such as the cerebral cortex. We have recently shown that a particular thalamic …

Corticofugal projections to neurons in the medullary dorsal horn, ie, the trigeminal spinal
subnucleus caudalis (Sp5C), are thought to play a critical role in regulating nociceptive …

The primary (S1) and secondary (S2) somatosensory cortices project to several trigeminal
sensory nuclei. One putative function of these corticofugal projections is the gating of …