Antibiotic exposure at the beginning of life can lead to increased antimicrobial resistance
and perturbations of the developing microbiome. Early-life microbiome disruption increases …

Coagulase-negative staphylococci (CoNS) are among the most frequently recovered
bacteria in routine clinical care. Their incidence has steadily increased over the past …

Importance In young febrile infants, serious bacterial infections (SBIs), including urinary tract
infections, bacteremia, and meningitis, may lead to dangerous complications. However …

Progress has been made in the reduction of morbidity and mortality from neonatal sepsis.
However, diagnosis continues to rely primarily on conventional microbiologic techniques …

Human healthcare is one of the most important topics for society. It tries to find the correct
effective and robust disease detection as soon as possible to patients receipt the …

Objectives Identifying infection aetiology is essential for appropriate antibiotic use. Previous
studies have shown that a host-protein signature consisting of TNF-related apoptosis …

Importance Induced hypothermia, the standard treatment for hypoxic-ischemic
encephalopathy (HIE) in high-income countries (HICs), is less effective in the low-income …

Rapid and accurate classification of the etiology for acute respiratory illness not only helps
establish timely therapeutic plans but also prevents inappropriate use of antibiotics. Host …

As the capacity for generating large-scale molecular profiling data continues to grow, the
ability to extract meaningful biological knowledge from it remains a limitation. Here, we …

Community-acquired pneumonia (CAP) is one of the most common serious infections in
childhood. This review focuses on pediatric CAP in the United States and other …