Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

AS Deshmukh, DE Steenberg, M Hostrup… - Nature …, 2021 - nature.com
Skeletal muscle conveys several of the health-promoting effects of exercise; yet the
underlying mechanisms are not fully elucidated. Studying skeletal muscle is challenging due …

Human muscle fiber type–specific insulin signaling: impact of obesity and type 2 diabetes

PH Albers, AJT Pedersen, JB Birk, DE Kristensen… - Diabetes, 2015 - Am Diabetes Assoc
Skeletal muscle is a heterogeneous tissue composed of different fiber types. Studies
suggest that insulin-mediated glucose metabolism is different between muscle fiber types …

TNF‐α‐mediated reduction in PGC‐1α may impair skeletal muscle function after cigarette smoke exposure

K Tang, PD Wagner, EC Breen - Journal of cellular physiology, 2010 - Wiley Online Library
Skeletal muscle dysfunction contributes to exercise limitation in COPD. In this study cigarette
smoke exposure was hypothesized to increase expression of the inflammatory cytokine, TNF …

Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component

E Kudryashova, J Wu, LA Havton… - Human molecular …, 2009 - academic.oup.com
Limb-girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy are
hereditary skeletal muscle disorders caused by mutations in TRIM32. We previously …

Global deletion of thrombospondin‐1 increases cardiac and skeletal muscle capillarity and exercise capacity in mice

MH Malek, IM Olfert - Experimental physiology, 2009 - Wiley Online Library
Thrombospondin‐1 (TSP‐1) is a known inhibitor of angiogenesis; however, a skeletal
muscle phenotype of TSP‐1 null mice has not been investigated. The purposes of this study …

Maximal lengthening contractions induce different signaling responses in the type I and type II fibers of human skeletal muscle

J Tannerstedt, W Apró… - Journal of applied …, 2009 - journals.physiology.org
The molecular mechanisms by which resistance exercise enlarges muscle mass, particularly
the mass of fast-twitch type II fibers, are likely to involve enhanced phosphorylation …

Protocol for high-resolution separation of rodent myosin heavy chain isoforms in a mini-gel electrophoresis system

W Mizunoya, J Wakamatsu, R Tatsumi, Y Ikeuchi - Analytical Biochemistry, 2008 - Elsevier
Skeletal muscle comprises several fiber types classified based on their contractile and
metabolic properties. Skeletal muscle fiber types are classified according to their myosin …

Modelling in vivo creatine/phosphocreatine in vitro reveals divergent adaptations in human muscle mitochondrial respiratory control by ADP after acute and chronic …

M Ydfors, MC Hughes, R Laham… - The Journal of …, 2016 - Wiley Online Library
Key points Mitochondrial respiratory sensitivity to ADP is thought to influence muscle fitness
and is partly regulated by cytosolic–mitochondrial diffusion of ADP or phosphate shuttling …

[HTML][HTML] Muscle fiber type and metabolic profiles of four muscles from the African black ostrich

TA Kohn, MJ Anley, NM S'thandiwe, L Adamson… - Meat Science, 2023 - Elsevier
Muscle fiber type, fiber cross-sectional area (CSA), enzyme activities (citrate synthase (CS),
3-hydroxyacetyl Co A dehydrogenase (3HAD), lactate dehydrogenase (LDH) and …

[HTML][HTML] Reduced glucose tolerance and skeletal muscle GLUT4 and IRS1 content in cyclists habituated to a long-term low-carbohydrate, high-fat diet

CC Webster, KM van Boom… - … journal of sport …, 2020 - journals.humankinetics.com
Very little is known about how long-term (> 6 months) adaptation to a low-carbohydrate, high-
fat (LCHF) diet affects insulin signaling in healthy, well-trained individuals. This study …