Cancer-related accelerated ageing and biobehavioural modifiers: a framework for research and clinical care

JE Carroll, JE Bower, PA Ganz - Nature Reviews Clinical Oncology, 2022 - nature.com
A growing body of evidence indicates that patients with cancer who receive cytotoxic
treatments (such as chemotherapy or radiotherapy) have an increased risk of accelerated …

[HTML][HTML] Telomere length and oxidative stress and its relation with metabolic syndrome components in the aging

G Gavia-García, J Rosado-Pérez, TL Arista-Ugalde… - Biology, 2021 - mdpi.com
Simple Summary A link between telomere length and some age-related diseases has been
identified, including metabolic syndrome. So far, there is no mechanism to explain the origin …

[HTML][HTML] Inverted U-shaped relationship between sleep duration and phenotypic age in US adults: a population-based study

Y You, Y Chen, R Liu, Y Zhang, M Wang, Z Yang… - Scientific Reports, 2024 - nature.com
Sleep is a modifiable behavior that can be targeted in interventions aimed at promoting
healthy aging. This study aims to (i) identify the sleep duration trend in US adults;(ii) …

[HTML][HTML] Effect of physical activity, smoking, and sleep on telomere length: a systematic review of observational and intervention studies

R Barragán, C Ortega-Azorín, JV Sorli… - Journal of clinical …, 2021 - mdpi.com
Aging is a risk factor for several pathologies, restricting one's health span, and promoting
chronic diseases (eg, cardiovascular and neurodegenerative diseases), as well as cancer …

[HTML][HTML] Circadian immunity from bench to bedside: a practical guide

H Mok, E Ostendorf, A Ganninger… - The Journal of …, 2024 - Am Soc Clin Investig
The immune system is built to counteract unpredictable threats, yet it relies on predictable
cycles of activity to function properly. Daily rhythms in immune function are an expanding …

[HTML][HTML] Cellular senescence in brain aging and cognitive decline

A Shafqat, S Khan, MH Omer, M Niaz… - Frontiers in aging …, 2023 - frontiersin.org
Cellular senescence is a biological aging hallmark that plays a key role in the development
of neurodegenerative diseases. Clinical trials are currently underway to evaluate the …

Obstructive sleep apnea and hallmarks of aging

LS Gaspar, AR Álvaro, J Moita, C Cavadas - Trends in molecular medicine, 2017 - cell.com
Obstructive sleep apnea (OSA) is one of the most common sleep disorders. Since aging is a
risk factor for OSA development, it is expected that its prevalence will increase with the …

Sleep duration and telomere length in children

S James, S McLanahan, J Brooks-Gunn… - The Journal of …, 2017 - Elsevier
Objective To test the association between sleep duration and telomere length in a pediatric
population. Study design We analyzed cross-sectional data for 1567 children from the age 9 …

[HTML][HTML] Mendelian randomization and colocalization analyses reveal an association between short sleep duration or morning chronotype and altered leukocyte …

J Hu, J Lu, Q Lu, W Weng, Z Guan, Z Wang - Communications Biology, 2023 - nature.com
Observational studies suggest certain sleep traits are associated with telomere length, but
the causal nature of these associations is unclear. The study aimed to determine the causal …

[HTML][HTML] Effects of chronic sleep deprivation on bone mass and bone metabolism in rats

X Xu, L Wang, L Chen, T Su, Y Zhang, T Wang… - Journal of orthopaedic …, 2016 - Springer
Background This study aimed to assess the effects of chronic sleep deprivation (CSD) on
bone mass and bone metabolism in rats. Methods Twenty-four rats were randomly divided …