Artificial muscles and soft robotic devices for treatment of end‐stage heart failure

A Weymann, J Foroughi, R Vardanyan… - Advanced …, 2023 - Wiley Online Library
Medical soft robotics constitutes a rapidly developing field in the treatment of cardiovascular
diseases, with a promising future for millions of patients suffering from heart failure …

Advances in novel devices for the treatment of heart failure

R Tang, Y Chang, J Song - Heart Failure Reviews, 2023 - Springer
Heart failure (HF) is one of the leading causes of global health impairment. Current drugs
are still limited in their effectiveness in the treatment and reversal of HF: for example, drugs …

Soft robotic patient-specific hydrodynamic model of aortic stenosis and ventricular remodeling

L Rosalia, C Ozturk, D Goswami, J Bonnemain… - Science robotics, 2023 - science.org
Aortic stenosis (AS) affects about 1.5 million people in the United States and is associated
with a 5-year survival rate of 20% if untreated. In these patients, aortic valve replacement is …

An image-driven micromechanical approach to characterize multiscale remodeling in infarcted myocardium

EA Mendiola, S Neelakantan, Q Xiang, S Xia, J Zhang… - Acta biomaterialia, 2024 - Elsevier
Myocardial infarction (MI) is accompanied by the formation of a fibrotic scar in the left
ventricle (LV) and initiates significant alterations in the architecture and constituents of the …

Robotic Cardiac Compression Device Using Artificial Muscle Filaments for the Treatment of Heart Failure

PT Phan, J Davies, TT Hoang, MT Thai… - Advanced Intelligent …, 2024 - Wiley Online Library
Heart failure occurs when the heart cannot pump adequate blood to the body, which afflicts
over 60 million people worldwide. Its treatment options include physiotherapy, medication …

The Future of Durable Mechanical Circulatory Support–Emerging Technological Innovations and Considerations to Enable Evolution of the Field

SA Dual, J Cowger, E Roche, A Nayak - Journal of Cardiac Failure, 2024 - Elsevier
The field of durable mechanical circulatory support (MCS) has undergone an incredible
evolution over the past few decades, resulting in significant improvements in longevity and …

Preclinical Proof-of-Concept of a Minimally Invasive Direct Cardiac Compression Device for Pediatric Heart Support

EC Hord, MP Hager, CM Bolch, K Bonugli… - Cardiovascular …, 2024 - Springer
Purpose For pediatric patients, extracorporeal membrane oxygenation (ECMO) remains the
predominant mechanical circulatory support (MCS) modality for heart failure (HF) although …

Myocardial Tissue Repair and Regeneration

K Wang, S Wang, Y Miao, Y Lu, H Zheng… - … Biomaterials for Tissue …, 2023 - Springer
Heart failure caused by myocardial infarction (MI) remains a major threat to human health.
After MI, a series of pathological events take place, including apoptosis of cardiac cells …

基于有限元方法的直接心室辅助加载模式研究

宸李, 贤杰强, 盛张, 天博王, 晓翰刘… - Sheng Wu Yi Xue …, 2024 - pmc.ncbi.nlm.nih.gov
为了研究直接心室辅助的生物力学影响以及探究最优的加载模式, 本文基于有限元方法建立了心
衰患者的左心室模型, 并提出了一种维持压迫力峰值的加载模式, 从血流动力学和生物力学两个 …

Tunable, soft robotics-enabled patient-specific hydrodynamic model of aortic stenosis and secondary ventricular remodeling

L Rosalia, C Ozturk, D Goswami, J Bonnemain… - medRxiv, 2022 - medrxiv.org
Aortic stenosis (AS) affects approximately 1.5 million people in the US and is associated with
a 5-year survival rate of 20% if untreated. In these patients, aortic valve replacement is …