Ischemic heart disease pathophysiology paradigms overview: from plaque activation to microvascular dysfunction

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …

Cardiac MRI Endpoints in Myocardial Infarction Experimental and Clinical Trials: JACC Scientific Expert Panel

B Ibanez, AH Aletras, AE Arai, H Arheden, J Bax… - Journal of the American …, 2019 - jacc.org
After a reperfused myocardial infarction (MI), dynamic tissue changes occur (edema,
inflammation, microvascular obstruction, hemorrhage, cardiomyocyte necrosis, and …

Pathophysiology and diagnosis of coronary microvascular dysfunction in ST-elevation myocardial infarction

LSF Konijnenberg, P Damman… - Cardiovascular …, 2020 - academic.oup.com
Early mechanical reperfusion of the epicardial coronary artery by primary percutaneous
coronary intervention (PCI) is the guideline-recommended treatment for ST-elevation …

Intra-aortic balloon counterpulsation and infarct size in patients with acute anterior myocardial infarction without shock: the CRISP AMI randomized trial

MR Patel, RW Smalling, H Thiele, HX Barnhart, Y Zhou… - Jama, 2011 - jamanetwork.com
Context Intra-aortic balloon counterpulsation (IABC) is an adjunct to revascularization in
patients with cardiogenic shock and reduces infarct size when placed prior to reperfusion in …

Prognostic significance and determinants of myocardial salvage assessed by cardiovascular magnetic resonance in acute reperfused myocardial infarction

I Eitel, S Desch, G Fuernau, L Hildebrand… - Journal of the American …, 2010 - jacc.org
Objectives: The aim of the study was to determine the prognostic significance and
determinants of myocardial salvage assessed by cardiovascular magnetic resonance (CMR) …

Cardiac MRI: a central prognostic tool in myocardial fibrosis

B Ambale-Venkatesh, JAC Lima - Nature Reviews Cardiology, 2015 - nature.com
Fibrotic remodelling of the extracellular matrix is a healing mechanism necessary
immediately after myocardial injury. However, prolonged increase in myocardial fibrotic …

Comparative prognostic utility of indexes of microvascular function alone or in combination in patients with an acute ST-segment–elevation myocardial infarction

D Carrick, C Haig, N Ahmed, J Carberry, VT Yue May… - Circulation, 2016 - Am Heart Assoc
Background: Primary percutaneous coronary intervention is frequently successful at
restoring coronary artery blood flow in patients with acute ST-segment–elevation myocardial …

Dynamic changes of edema and late gadolinium enhancement after acute myocardial infarction and their relationship to functional recovery and salvage index

E Dall'Armellina, N Karia, AC Lindsay… - Circulation …, 2011 - Am Heart Assoc
Background—Changes in the myocardium in acute ischemia are dynamic and complex, and
the characteristics of myocardial tissue on cardiovascular magnetic resonance in the acute …

[HTML][HTML] T2-weighted cardiovascular magnetic resonance in acute cardiac disease

I Eitel, MG Friedrich - Journal of Cardiovascular Magnetic Resonance, 2011 - Elsevier
Cardiovascular magnetic resonance (CMR) using T2-weighted sequences can visualize
myocardial edema. When compared to previous protocols, newer pulse sequences with …

Prognostic value and determinants of a hypointense infarct core in T2-weighted cardiac magnetic resonance in acute reperfused ST-elevation–myocardial infarction

I Eitel, K Kubusch, O Strohm, S Desch… - Circulation …, 2011 - Am Heart Assoc
Background—A hypointense core of infarcted myocardium in T2-weighted cardiovascular
MRI (CMR) has been used as a noninvasive marker for intramyocardial hemorrhage …