Recent advances in poor HIV immune reconstitution: what will the future look like?

W Zhang, L Ruan - Frontiers in Microbiology, 2023 - frontiersin.org
Combination antiretroviral therapy has demonstrated proved effectiveness in suppressing
viral replication and significantly recovering CD4+ T cell count in HIV type-1 (HIV-1)-infected …

MAIT cells altered phenotype and cytotoxicity in lupus patients are linked to renal disease severity and outcome

E Litvinova, C Bounaix, G Hanouna, J Da Silva… - Frontiers in …, 2023 - frontiersin.org
Introduction Systemic lupus erythematosus (SLE) is an autoimmune disease in which
circulating immune complexes can cause different types of glomerulonephritis, according to …

[HTML][HTML] Immunomodulation with IL-7 and IL-15 in HIV-1

JD Gunst, N Goonetilleke, TA Rasmussen… - Journal of Virus …, 2023 - Elsevier
Immunomodulating agents are substances that modify the host immune response in
diseases such as infections, autoimmune conditions and cancers. Immunomodulators can …

IL-7 Promotes the Expansion of Circulating CD28- Cytotoxic T Lymphocytes in Patients With IgG4-Related Disease via the JAK Signaling

C Xia, Y Long, Y Liu, A Alifu, X Zeng, C Liu - Frontiers in Immunology, 2022 - frontiersin.org
Objectives This study aimed to elucidate the changes and associated mechanisms of
circulating CD28-cytotoxic T lymphocytes (CTLs) in patients with IgG4-related disease (IgG4 …

Interleukin-7 regulates CD127 expression and promotes CD8+ T cell activity in patients with primary cutaneous melanoma

H He, B Qiao, S Guo, H Cui, Z Zhang, J Qin - BMC immunology, 2022 - Springer
Abstract Background Interleukin (IL)-7 signaling through CD127 is impaired in lymphocytes
in cancers and chronic infections, resulting in CD8+ T cell exhaustion. The mechanisms …