Active pharmaceutical ingredient (API) chemicals: a critical review of current biotechnological approaches

V Kumar, V Bansal, A Madhavan, M Kumar… - …, 2022 - Taylor & Francis
The aim of this article was to generate a framework of bio-based economy by an effective
utilization of biomass from the perspectives of agriculture for developing potential end bio …

Overview on the hydrodynamic conditions found in industrial systems and its impact in (bio) fouling formation

S Fernandes, IB Gomes, LC Simões… - Chemical Engineering …, 2021 - Elsevier
Biofouling is the unwanted accumulation of deposits on surfaces, composed by organic and
inorganic particles and (micro) organisms. Its occurrence in industrial equipment is …

Anoxic biogas biodesulfurization promoting elemental sulfur production in a Continuous Stirred Tank Bioreactor

JJ González-Cortés, S Torres-Herrera… - Journal of Hazardous …, 2021 - Elsevier
Biological desulfurization of biogas has been extensively studied using biotrickling filters
(BTFs). However, the accumulation of elemental sulfur (S°) on the packing material limits the …

Disposable rocking bioreactors: recent applications and progressive perspectives

K Wierzchowski, M Pilarek - Trends in Biotechnology, 2024 - cell.com
Disposable rocking bioreactors facilitate scaling up animal and plant cell biomass
propagation and developing specified bioprocesses like manufacturing vaccines or chimeric …

[HTML][HTML] Controlling Aspergillus niger morphology in a low shear-force environment in a rocking-motion bioreactor

T Kheirkhah, P Neubauer, S Junne - Biochemical Engineering Journal, 2023 - Elsevier
The filamentous fungus Aspergillus niger is an important production host in biotechnology.
Shear force regimes are one of the key factors that affect macromorphology and product …

CFD modelling of a wave-mixed bioreactor with complex geometry and two degrees of freedom motion

S Seidel, RW Maschke, M Kraume, R Eibl… - Frontiers in Chemical …, 2022 - frontiersin.org
Optimizing bioprocesses requires an in-depth understanding, from a bioengineering
perspective, of the cultivation systems used. A bioengineering characterization is typically …

Clavulanic Acid Production by Streptomyces clavuligerus: Insights from Systems Biology, Strain Engineering, and Downstream Processing

VA López-Agudelo, D Gómez-Ríos, H Ramirez-Malule - Antibiotics, 2021 - mdpi.com
Clavulanic acid (CA) is an irreversible β-lactamase enzyme inhibitor with a weak
antibacterial activity produced by Streptomyces clavuligerus (S. clavuligerus). CA is typically …

Double-ring epimerization in the biosynthesis of clavulanic acid

S Gómez, H Ramírez-Malule… - The Journal of …, 2020 - ACS Publications
All reaction steps during the biosynthesis of suicidal clavulanic acid (coformulated with β-
lactam antibiotics and used to fight bacterial infections) are known, except for the crucial 3S …

Single‐use Technology for the Production of Cellular Agricultural Products: Where are We Today?

C Schirmer, R Eibl, RW Maschke… - Chemie Ingenieur …, 2022 - Wiley Online Library
Single‐use Technology for the Production of Cellular Agricultural Products: Where are We
Today? - Schirmer - 2022 - Chemie Ingenieur Technik - Wiley Online Library Skip to Article …

Pasteurellosis Vaccine Commercialization: Physiochemical Factors for Optimum Production

SNH Oslan, JS Tan, AH Yusoff, AZ Sulaiman… - Processes, 2022 - mdpi.com
Pasteurella spp. are Gram-negative facultative bacteria that cause severe economic and
animal losses. Pasteurella-based vaccines are the most promising solution for controlling …