Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives

S Regmi, S Pathak, JO Kim, CS Yong… - European journal of cell …, 2019 - Elsevier
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

Mesenchymal stromal cells (MSCs) and their exosome in acute liver failure (ALF): a comprehensive review

S Shokravi, V Borisov, BA Zaman, F Niazvand… - Stem Cell Research & …, 2022 - Springer
Recently, mesenchymal stromal cells (MSCs) and their derivative exosome have become a
promising approach in the context of liver diseases therapy, in particular, acute liver failure …

Regenerative potential of Wharton's jelly‐derived mesenchymal stem cells: A new horizon of stem cell therapy

H Abbaszadeh, F Ghorbani… - Journal of Cellular …, 2020 - Wiley Online Library
Umbilical cord Wharton's jelly‐derived mesenchymal stem cells (WJ‐MSCs) have recently
gained considerable attention in the field of regenerative medicine. Their high proliferation …

Umbilical cord mesenchymal stromal cells—from bench to bedside

S Chetty, R Yarani, G Swaminathan… - Frontiers in Cell and …, 2022 - frontiersin.org
In recent years, mesenchymal stromal cells (MSCs) have generated a lot of attention due to
their paracrine and immuno-modulatory properties. mesenchymal stromal cells derived from …

Effects of adipose derived stem cells pretreated with resveratrol on sciatic nerve regeneration in rats

Z Zhang, M Zhang, Y Sun, M Li, C Chang, W Liu… - Scientific Reports, 2023 - nature.com
Adipose derived stem cells (ADSCs) are popular in regenerative medicine due to their easy
availability, low immunogenicity and lack of controversy regarding their ethical debate use …

Potential networks regulated by MSCs in acute-on-chronic liver failure: exosomal miRNAs and intracellular target genes

J Zhang, J Gao, D Lin, J Xiong, J Wang, J Chen… - Frontiers in …, 2021 - frontiersin.org
Acute-on-chronic liver failure (ACLF) is a severe syndrome associated with high mortality.
Alterations in the liver microenvironment are one of the vital causes of immune damage and …

Human Wharton's Jelly-derived mesenchymal stem cells prevent acetaminophen-induced liver injury in a mouse model unlike human dermal fibroblasts

DS Umbaugh, RP Soder, NT Nguyen, O Adelusi… - Archives of …, 2022 - Springer
The persistence of hepatotoxicity induced by N-acetyl-para-aminophenol (Acetaminophen
or Paracetamol, abbreviated as APAP) as the most common cause of acute liver failure in …

Comparison of the Efficacy of Two Routes of Administration of Human Amniotic Epithelial Cells in Cell Therapy of Acute Hepatic Insufficiency

P Wieczorek, P Czekaj, M Król, E Bogunia, M Hermyt… - Pharmaceuticals, 2024 - mdpi.com
The route of administration of implanted cells may affect the outcome of cell therapy by
directing cell migration to the damaged site. However, the question of the relationship …

Assessment of animal experimental models of toxic liver injury in the context of their potential application as preclinical models for cell therapy

P Czekaj, M Król, Ł Limanówka, M Michalik… - European journal of …, 2019 - Elsevier
Preclinical animal models allow to study development and progression of several diseases,
including liver disorders. These studies, for ethical reasons and medical limits, are …

[HTML][HTML] Dynamics of acute liver injury in experimental models of hepatotoxicity in the context of their implementation in preclinical studies on stem cell therapy

P Czekaj, M Król, Ł Limanówka… - Frontiers in Bioscience …, 2022 - imrpress.com
Background and Aims: Experimental models using carbon tetrachloride (CCl4) and D-
galactosamine (D-GalN) can be used in preclinical assessment of acute liver failure (ALF) …