Emerging insights into pyrazoline motifs: A comprehensive exploration of biological mechanisms and prospects for future advancements

HA Abou-Zied, EAM Beshr, AM Hayallah… - Journal of Molecular …, 2024 - Elsevier
The prevalence of cancer and neurodegenerative diseases, such as Alzheimer's and
Parkinson's, continues to rise worldwide, presenting a significant health burden. Despite …

Medicinal Attributes of Pyrazoline in Drug Discovery

D Arora, J Singh, S Kumar - Letters in Drug Design & Discovery, 2024 - benthamdirect.com
Pyrazoline are structurally versatile nitrogen-containing heterocycle that has gained more
attention owing to its diversified pharmacological activities. This special scaffold serves as a …

Mouse strain-specific habituation to oral metamizole administration

T Schreiber, E Leitner, J Brandstetter… - Laboratory …, 2024 - journals.sagepub.com
When pain might occur during an animal experiment, sufficient analgesia is necessary.
Metamizole is the third most used postoperative pain medication in animal research. The …

[HTML][HTML] Effects of Metamizole, 4-Methylaminoantipyrine, and 4-Aminoantipyrine on LX-2 Liver Cell Line Viability and Apoptosis

GI Lupu, E Pall, M Cenariu, MI Nan, S Andrei - Molecules, 2024 - mdpi.com
Metamizole (dipyrone) is a non-opioid analgesic widely used in human and veterinary
medicine, despite ongoing concerns about its safety due to risks such as agranulocytosis …

Pharmacotherapeutic monitoring of dipyrone in northeastern Brazilian donkeys (Equus asinus)

KN Arcoverde, L de Sant, A Alves… - Research in Veterinary …, 2023 - Elsevier
This study aimed to monitor the effects of dipyrone following multiple administrations in
northeastern donkeys. Ten castrated male donkeys, aged 6.4±3 years and weighing …

[HTML][HTML] Metamizole in the Management of Musculoskeletal Disorders: Current Concept Review

N Jeyaraman, F Migliorini, S Murugan… - Journal of Clinical …, 2024 - mdpi.com
Metamizole, or dipyrone, has been used for decades as a non-narcotic analgesic, providing
pain relief from musculoskeletal disorders and antipyretic and antispasmolytic properties …

Doença degenerativa do disco intervertebral e extrusão discal toracolombar em cães

JRA Almeida - 2024 - dspace.uevora.pt
O presente relatório surge na sequência do estágio curricular do Mestrado Integrado em
Medicina Veterinária, realizado no Hospital Veterinário Tutivete, Santarém, Portugal, entre …

Cuidados y precauciones de la terapéutica con antibióticos y analgésicos en pacientes en medicina veterinaria de pequeñas especies

V Sandoval Cuevas - 2023 - repository.ucc.edu.co
La insuficiencia renal es la patología renal más frecuentes en caninos y felinos, esta se
define como las alteraciones estructurales o funcionales de uno o de ambos riñones. A …

[PDF][PDF] Evaluation of antinociceptive and sedative effects of methadone or morphine in combination with ketamine-midazolam in Oryctolagus cuniculus (Linnaeus …

GS Júnior, AB Riva, DS Cipriani, KM Fernandes… - researchgate.net
Author for correspondence email: Gilberto Serighelli Júnior–gilberto. serighelli@ ufpr. br
Abstract: The objective of this study was to evaluate the effect of adding methadone or …

[引用][C] TREATMENT FOR TRANSMISSIBLE VENEREAL TUMOR IN FEMALE DOG WITH TUMOR EXCISION THROUGH EPISIOTOMY APPROACH

YR Sari, IGAGP Pemayun, IW Gorda - Veterinary Science and Medicine Journal, 2023