Dietary flavonoids: Cardioprotective potential with antioxidant effects and their pharmacokinetic, toxicological and therapeutic concerns

J Khan, PK Deb, S Priya, KD Medina, R Devi… - Molecules, 2021 - mdpi.com
Flavonoids comprise a large group of structurally diverse polyphenolic compounds of plant
origin and are abundantly found in human diet such as fruits, vegetables, grains, tea, dairy …

The effect of dietary polyphenols on vascular health and hypertension: current evidence and mechanisms of action

G Grosso, J Godos, W Currenti, A Micek, L Falzone… - Nutrients, 2022 - mdpi.com
The aim of this review was to explore existing evidence from studies conducted on humans
and summarize the mechanisms of action of dietary polyphenols on vascular health, blood …

Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease

Q Yan, S Liu, Y Sun, C Chen, S Yang, M Lin… - Journal of Translational …, 2023 - Springer
Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …

Resveratrol-like compounds as SIRT1 activators

L Ciccone, E Piragine, S Brogi, C Camodeca… - International Journal of …, 2022 - mdpi.com
The sirtuin 1 (SIRT1) activator resveratrol has emerged as a promising candidate for the
prevention of vascular oxidative stress, which is a trigger for endothelial dysfunction …

Lipid oxidation products on inflammation-mediated hypertension and atherosclerosis: A mini review

XF Leong - Frontiers in Nutrition, 2021 - frontiersin.org
Cardiovascular diseases such as hypertension and atherosclerosis are the common causes
of mortality in developed and developing countries. Repeated heating of the dietary oil is a …

[HTML][HTML] Naringin suppressed airway inflammation and ameliorated pulmonary endothelial hyperpermeability by upregulating Aquaporin1 in lipopolysaccharide …

H Zhang, X Zhou, Y Zhong, L Ji, W Yu, J Fang… - Biomedicine & …, 2022 - Elsevier
Naringin is one of the natural flavonoids extracted from many Chinese medicines. It
ameliorates endothelial dysfunctions in atherosclerosis, diabetes, and cardiovascular …

[HTML][HTML] (Poly) phenols and the regulation of NADPH oxidases

CG Fraga, PI Oteiza, EJ Hid, M Galleano - Redox Biology, 2023 - Elsevier
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are enzymes that
generate superoxide anion (O 2•-) and hydrogen peroxide (H 2 O 2), and that are widely …

Naringin ameliorates skeletal muscle atrophy and improves insulin resistance in high-fat-diet-induced insulin resistance in obese rats

C Termkwancharoen, W Malakul, A Phetrungnapha… - Nutrients, 2022 - mdpi.com
Obesity causes progressive lipid accumulation and insulin resistance within muscle cells
and affects skeletal muscle fibres and muscle mass that demonstrates atrophy and …

Naringin attenuates fructose-induced NAFLD progression in rats through reducing endogenous triglyceride synthesis and activating the Nrf2/HO-1 pathway

S Pengnet, P Sumarithum, N Phongnu… - Frontiers in …, 2022 - frontiersin.org
Background: Excessive fructose consumption causes hepatic lipid accumulation via
increased triglyceride (TG) synthesis, leading to the development and progression of non …

Protein tyrosine nitration in atherosclerotic endothelial dysfunction

M Jiang, XM Zhao, ZS Jiang, GX Wang, D Zhang - Clinica Chimica Acta, 2022 - Elsevier
Accumulation of reactive oxygen species (ROS) can induce both protein tyrosine nitration
and endothelial dysfunction in atherosclerosis. Endothelial dysfunction refers to impaired …