Alzheimer's Disease (AD) is one of the most devastating age-related disorder causing
significant social and economic burden worldwide. It affects the cognitive and social …

Parkinson's Disease (PD) remains a significant focus of extensive research aimed at
developing effective therapeutic strategies. Current treatments primarily target symptom …

Introduction The inositol polyphosphate‐5‐phosphatase D (INPP5D) gene encodes a dual‐
specificity phosphatase that can dephosphorylate both phospholipids and phosphoproteins …

We report herein the potential of colony-stimulating factor-1 receptor (CSF1R) inhibitors as
therapeutic agents in neuroinflammatory diseases, with a focus on Alzheimer's disease …

This study explores the potential of CSF-1R inhibitors as therapeutic agents for
neurodegenerative diseases. CSF-1R, a receptor tyrosine kinase primarily expressed in …

In acute neuroinflammation, microglia activate transiently, and return to a resting state later
on. However, they may retain immune memory of such event, namely priming. Primed …

Background Microglia, a type of resident immune cells within the central nervous system,
have been implicated in ethanol-activated neuronal death of the stress regulatory …

Backgruond Melanoma is a common cancer in dermatology, but its molecular mechanisms
remain poorly explained. Aim Utilizing single-cell analytics and bioinformatics, the work …

Objective: To describe two novel heterozygous splicing variants of the CSF1R gene
responsible for CSF1R-microglial encephalopathy in two unrelated Han Chinese families …

Purpose Anti-gamma-aminobutyric acid B receptor (GABA BR) encephalitis is an uncommon
form of autoimmune encephalitis associated with a poor prognosis and a high fatality rate …