Synthetic chemicals with endocrine disrupting properties are pervasive in the environment
and are present in the bodies of humans and wildlife. As thyroid hormones (THs) control …

Maternal hypothyroxinemia can induce neurodevelopmental impairments in the developing
fetus. We here review recent studies on the epidemiology and molecular mechanisms …

Hyperthyroidism has been identified as a risk factor for cognitive disorders. The
hippocampus is a key brain region associated with cognitive function, among which …

Background The prevalence of autism spectrum disorder (ASD) has significantly risen in the
past three decades, prompting researchers to explore the potential contributions of …

It is well documented that thyroid hormone (TH) action is critical for normal brain
development and is mediated by both nuclear and extranuclear pathways. Given this …

Though there were many studies assessing the relationship between maternal thyroxine
levels during pregnancy and cognitive development in children, there was still lack of …

Iodine deficiency (ID)-induced thyroid hormone (TH) insufficient during development leads
to impairments of brain function, such as learning and memory. Marginal ID has been …

Background We aimed to study the role of amino-3-hydroxy-5-methylisoxazole-4-propionic
acid receptor (AMPAR) glutamate receptor 2 (GluR2) subunit trafficking, and activity …

The expression of homosynaptic long-term depression (LTD) governs the subsequent
induction of long-term potentiation (LTP) at hippocampal synapses. This process, called …

Abstract The principles of Predictive, Preventive and Personalized Medicine (PPPM) dictate
the need to recognize individual susceptibility to disease in a timely fashion and to offer …