Background: Obsessive-compulsive disorder (OCD) is associated with affective and
cognitive symptoms causing personal distress and reduced global functioning. These have …

In this position statement, developed by The International College of Obsessive-Compulsive
Spectrum Disorders, a group of international experts responds to recent developments in the …

Serotonin reuptake inhibitor (SRI) medications are well established as first-line
pharmacotherapeutic treatment for Obsessive-Compulsive Disorder (OCD). However …

Compulsions are repetitive, stereotyped thoughts and behaviors designed to reduce harm.
Growing evidence suggests that the neurocognitive mechanisms mediating behavioral …

Glutamate is a ubiquitous excitatory neurotransmitter, which is involved in normal
physiology, a variety of central nervous system (CNS) functions, including excitotoxicity and …

Objective: Obsessive-compulsive disorder (OCD) is a mental disease commonly associated
with severe distress and impairment of social functioning. Serotonin reuptake inhibitors …

Even though obsessive compulsive disorder (OCD) is one of the ten most disabling
diseases according to the WHO, only 30–40% of patients suffering from OCD seek …

Methods This systematic review aims to investigate the effects of ketamine in OCD, following
the Preferred Reporting Items for Systematic Review and Meta-analyses Protocols (PRISMA …

Background Various agents for augmentation of serotonin reuptake inhibitors have been
investigated for treatment-resistant obsessive-compulsive disorder (OCD). We aimed to …

Abstract Treatment-resistance is a frequent condition for obsessive-compulsive disorder
(OCD). Over the past decades, a lot of effort has been made to address this issue, and …