During the past two decades, nitric oxide (NO) has been recognized as one of the most
versatile players in the immune system. It is involved in the pathogenesis and control of …

Bacterial sepsis and septic shock result from the overproduction of inflammatory mediators
as a consequence of the interaction of the immune system with bacteria and bacterial wall …

It has been known for many years that neutrophils and platelets participate in the
pathogenesis of severe sepsis, but the inter-relationship between these players is …

Nitric oxide (NO) is a colorless gas at room temperature and one of the simplest molecules
known, yet it has been implicated in a wide variety of regulatory mechanisms ranging from …

Well over 2 decades have passed since the endothelium-derived relaxation factor was
reported to be the gaseous molecule nitric oxide (NO). Although soluble guanylyl cyclase …

Lung ischemia-reperfusion injury remains one of the major complications after cardiac
bypass surgery and lung transplantation. Due to its dual blood supply system and the …

Fire sweeps through the brush. In its aftermath, dormant seeds of chaparral, savanna, heath,
and scrub begin to germinate in response to a “go” signal in the smoke. Even though …

Epithelial and other cells of the gastrointestinal mucosa rely on both luminal and
bloodstream sources for their nutrition. The term functional food is used to describe nutrients …

Nitric oxide (NO) is an intra-and inter-signaling molecule that regulates vessel dilatation,
neuronal transmission, cardiac contraction, immunomodulation, and stem cell differentiation …

The rapid and selective accumulation of neutrophils into the lungs is thought to underlie the
pulmonary failure that leads to sepsis-related death. In this study we investigated whether …