Lactoferrin: An overview of its main functions, immunomodulatory and antimicrobial role, and clinical significance

M Sienkiewicz, A Jaśkiewicz, A Tarasiuk… - Critical reviews in food …, 2022 - Taylor & Francis
Lactoferrin (LF), a glycoprotein found in mucosal secretions, is characterized by a wide
range of functions, including immunomodulatory and anti-inflammatory activities. Moreover …

Neuroprotective effects of lactoferrin in Alzheimer's and Parkinson's diseases: A narrative review

SJ Yong, A Veerakumarasivam, WL Lim… - ACS Chemical …, 2023 - ACS Publications
Recent advancements in lactoferrin research have uncovered that lactoferrin does function
not only as an antimicrobial protein but also as an immunomodulatory, anticancer, and …

Lactoferrin for prevention and treatment of anemia and inflammation in pregnant women: A comprehensive review

J Artym, M Zimecki, ML Kruzel - Biomedicines, 2021 - mdpi.com
Pregnancy is a physiological state that demands higher level of nutrients, including vitamins
and minerals, for the growth and maintenance of the fetus. Iron deficiency is a part of most …

Cellular agriculture for milk bioactive production

L Yart, AW Wijaya, MJ Lima, C Haller… - Nature Reviews …, 2023 - nature.com
Cellular agriculture, that is, the cell culture-based production of food, may provide an
alternative to traditional farming, minimizing the environmental effect, while ensuring …

Effects of dietary supplementation of bovine lactoferrin on growth performance, immune function and intestinal health in weaning piglets

X Ma, Y Hao, R Mao, N Yang, X Zheng, B Li, Z Wang… - Biometals, 2023 - Springer
Weaning is a crucial period in the pig's life cycle, which is frequently followed by
gastrointestinal (GI) infections, diarrhea and even death. This study focused on the impact of …

Lactoferrin, Osteopontin and Lactoferrin–Osteopontin Complex: A Critical Look on Their Role in Perinatal Period and Cardiometabolic Disorders

E Levy, V Marcil, S Tagharist Ép Baumel, N Dahan… - Nutrients, 2023 - mdpi.com
Milk-derived bioactive proteins have increasingly gained attention and consideration
throughout the world due to their high-quality amino acids and multiple health-promoting …

Dose-Dependent Neuroprotective Effects of Bovine Lactoferrin Following Neonatal Hypoxia–Ischemia in the Immature Rat Brain

E Sanches, Y van de Looij, S Sow, A Toulotte… - Nutrients, 2021 - mdpi.com
Injuries to the developing brain due to hypoxia–ischemia (HI) are common causes of
neurological disabilities in preterm babies. HI, with oxygen deprivation to the brain or …

Neuroprotective role of lactoferrin during early brain development and injury through lifespan

GH Schirmbeck, S Sizonenko, EF Sanches - Nutrients, 2022 - mdpi.com
Early adverse fetal environments can significantly disturb central nervous system (CNS)
development and subsequently alter brain maturation. Nutritional status is a major variable …

[HTML][HTML] Lactoferrin as a Versatile Agent in Nanoparticle Applications: From Therapeutics to Agriculture

E Akdaşçi, F Eker, H Duman, P Singh, M Bechelany… - Nanomaterials, 2024 - mdpi.com
Nanoparticles (NPs) have emerged as a potent choice for various applications, from drug
delivery to agricultural studies, serving as an alternative and promising methodology for …

The impact of complexation or complex coacervation of lactoferrin and osteopontin on simulated infant gastrointestinal digestion, intestinal inflammation, and in vivo …

DA Goulding, N Bonnet, MN Horcajada, M Baruchet… - Food & Function, 2024 - pubs.rsc.org
Lactoferrin (LF) and osteopontin (OPN) are bioactive milk proteins which can form
heteroprotein complexes and complex coacervates. This research studied the effect of LF …