Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

Dysfunction of the salivary gland and irreversible hyposalivation are the main side effects of
radiotherapy treatment for head and neck cancer leading to a drastic decrease of the quality …

Glandular epithelia, including the mammary and prostate glands, are composed of basal
cells (BCs) and luminal cells (LCs),. Many glandular epithelia develop from multipotent …

Salivary glands act as virus reservoirs in various infectious diseases and have been
reported to be targeted by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Understanding the dynamic transcriptional landscape throughout organ development will
provide a template for regenerative therapies. Here, we generated a single-cell RNA …

Salivary gland (SG) dysfunction, due to radiotherapy, disease, or aging, is a clinical
manifestation that has the potential to cause severe oral and/or systemic diseases and …

The mechanisms that prevent regeneration of irradiated (IR) salivary glands remain elusive.
Bulk RNAseq of IR versus non-IR human salivary glands showed that neurotrophin …

Permanent damage to the salivary glands and resulting hyposalivation and xerostomia have
a substantial impact on patient health, quality of life, and healthcare costs. Currently, patients …

Salivary gland (SG) dysfunction impairs the life quality of many patients, such as patients
with radiation therapy for head and neck cancer and patients with Sjögren's syndrome …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is primarily transmitted
through droplets. All human tissues with the angiotensin‐converting enzyme 2 (ACE2) and …