Clinical review: adiponectin biology and its role in inflammation and critical illness
K Robinson, J Prins, B Venkatesh - Critical Care, 2011 - Springer
Adiponectin is an adipokine first described just over a decade ago. Produced almost
exclusively by adipocytes, adiponectin circulates in high concentrations in human plasma …
exclusively by adipocytes, adiponectin circulates in high concentrations in human plasma …
T cells and their immunometabolism: A novel way to understanding sepsis immunopathogenesis and future therapeutics
V Kumar - European journal of cell biology, 2018 - Elsevier
Sepsis has always been considered as a big challenge for pharmaceutical companies in
terms of discovering and designing new therapeutics. The pathogenesis of sepsis involves …
terms of discovering and designing new therapeutics. The pathogenesis of sepsis involves …
Effects of DHA-enriched fish oil on gene expression levels of p53 and NF-κB and PPAR-γ activity in PBMCs of patients with T2DM: A randomized, double-blind, clinical …
Z Naeini, O Toupchian, A Vatannejad… - Nutrition, Metabolism …, 2020 - Elsevier
Abstract Background and Aims Omega-3 polyunsaturated fatty acids (PUFAs) are natural
peroxisome proliferator-activated receptor gamma (PPAR-γ) ligands. Activated PPAR-γ …
peroxisome proliferator-activated receptor gamma (PPAR-γ) ligands. Activated PPAR-γ …
Early and dynamic changes in gene expression in septic shock patients: a genome-wide approach
MA Cazalis, A Lepape, F Venet, F Frager… - Intensive care medicine …, 2014 - Springer
Background As early and appropriate care of severe septic patients is associated with better
outcome, understanding of the very first events in the disease process is needed. Pan …
outcome, understanding of the very first events in the disease process is needed. Pan …
Pioglitazone reduces inflammation through inhibition of NF-κB in polymicrobial sepsis
J Kaplan, M Nowell, R Chima, B Zingarelli - Innate immunity, 2014 - journals.sagepub.com
The insulin sensitizing thiazolidinedione drugs, rosiglitazone and pioglitazone are specific
peroxisome proliferator-activated receptor-gamma agonists and reduce pro-inflammatory …
peroxisome proliferator-activated receptor-gamma agonists and reduce pro-inflammatory …
[HTML][HTML] Adipokines in critical illness: A review of the evidence and knowledge gaps
E Alipoor, FM Hosseinzadeh… - Biomedicine & …, 2018 - Elsevier
Adipose tissue products or adipokines play a major role in chronic endocrine and metabolic
disorders; however, little is known about critical conditions. In this article, the experimental …
disorders; however, little is known about critical conditions. In this article, the experimental …
Alterations of dendritic cells in sepsis: featured role in immunoparalysis
X Fan, Z Liu, H Jin, J Yan… - BioMed Research …, 2015 - Wiley Online Library
Sepsis, the leading cause of mortality in intensive care unit, is characterized by
hyperinflammatory response in the early stage and followed by a period of …
hyperinflammatory response in the early stage and followed by a period of …
[HTML][HTML] Plasma as a resuscitation fluid for volume‐depleted shock: potential benefits and risks
DP van den Brink, DJB Kleinveld, PH Sloos… - Transfusion, 2021 - ncbi.nlm.nih.gov
The clinical state of shock constitutes a relative or absolute deficiency of circulating volume
for adequate oxygen delivery to meet the metabolic demands. 1 Although shock states differ …
for adequate oxygen delivery to meet the metabolic demands. 1 Although shock states differ …
Kinetics of circulating fetuin-A may predict mortality independently from adiponectin, high molecular weight adiponectin and prognostic factors in critically ill patients …
I Karampela, E Kandri, G Antonakos, E Vogiatzakis… - Journal of critical …, 2017 - Elsevier
Purpose Fetuin-A and adiponectin, major hepatokine and adipokine respectively, have been
implicated in systematic inflammation. Our aim was to jointly investigate whether kinetics of …
implicated in systematic inflammation. Our aim was to jointly investigate whether kinetics of …
Serial changes in adiponectin and resistin in critically ill patients with sepsis: associations with sepsis phase, severity, and circulating cytokine levels
PURPOSE: The aim of the present study was to describe the variation in adiponectin and
resistin levels, 2 adipokines with opposing effects on metabolism, in mechanically ventilated …
resistin levels, 2 adipokines with opposing effects on metabolism, in mechanically ventilated …