Emerging applications of metabolomics in drug discovery and precision medicine

DS Wishart - Nature reviews Drug discovery, 2016 - nature.com
Metabolomics is an emerging'omics' science involving the comprehensive characterization
of metabolites and metabolism in biological systems. Recent advances in metabolomics …

NMR and metabolomics—A roadmap for the future

DS Wishart, LL Cheng, V Copié, AS Edison… - Metabolites, 2022 - mdpi.com
Metabolomics investigates global metabolic alterations associated with chemical, biological,
physiological, or pathological processes. These metabolic changes are measured with …

High‐throughput metabolomics by 1D NMR

A Vignoli, V Ghini, G Meoni, C Licari… - Angewandte Chemie …, 2019 - Wiley Online Library
Metabolomics deals with the whole ensemble of metabolites (the metabolome). As one of
the‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …

Analytical methods in untargeted metabolomics: state of the art in 2015

A Alonso, S Marsal, A Julià - Frontiers in bioengineering and …, 2015 - frontiersin.org
Metabolomics comprises the methods and techniques that are used to measure the small
molecule composition of biofluids and tissues, and is actually one of the most rapidly …

NMR metabolomics: A look ahead

DS Wishart - Journal of Magnetic Resonance, 2019 - Elsevier
NMR has been used to perform metabolic studies, metabolic profiling and metabolomics in
biofluids and tissues for more than 40 years. This close connection between metabolic …

A review on the enzymes and metabolites identified by mass spectrometry from bacteria and microalgae involved in the degradation of high molecular weight PAHs

MM García, MPG de Llasera - Science of the Total Environment, 2021 - Elsevier
High molecular weight PAHs (HMW PAHs) are dangerous pollutants widely distributed in
the environment. The use of microorganisms represents an important tool for HMW PAHs …

Probiotic or synbiotic alters the gut microbiota and metabolism in a randomised controlled trial of weight management in overweight adults

AA Hibberd, CC Yde, ML Ziegler… - Beneficial …, 2019 - wageningenacademic.com
The gut microbiota contributes to host energy metabolism, and altered gut microbiota has
been associated with obesity-related metabolic disorders. We previously reported that a …

NMR spectroscopy for metabolomics and metabolic profiling

CK Larive, GA Barding Jr, MM Dinges - Analytical chemistry, 2015 - ACS Publications
Applications of NMR for metabolomics and metabolic profiling continue to grow rapidly as
does the refinement of methods for the measurement, analysis, and interpretation of …

Quantitative NMR-based biomedical metabolomics: Current status and applications

AA Crook, R Powers - Molecules, 2020 - mdpi.com
Nuclear Magnetic Resonance (NMR) spectroscopy is a quantitative analytical tool
commonly utilized for metabolomics analysis. Quantitative NMR (qNMR) is a field of NMR …

Mass spectrometry techniques in emerging pathogens studies: COVID-19 perspectives

I Mahmud, TJ Garrett - Journal of the American Society for Mass …, 2020 - ACS Publications
As corona virus disease 2019 (COVID-19) is a rapidly growing public health crisis across the
world, our knowledge of meaningful diagnostic tests and treatment for severe acute …