Troponin: the biomarker of choice for the detection of cardiac injury

L Babuin, AS Jaffe - Cmaj, 2005 - Can Med Assoc
It has been known for 50 years that transaminase activity increases in patients with acute
myocardial infarction. With the development of creatine kinase (CK), biomarkers of cardiac …

Pathophysiology of meningococcal meningitis and septicaemia

N Pathan, SN Faust, M Levin - Archives of disease in childhood, 2003 - adc.bmj.com
Neisseria meningitidis is remarkable for the diversity of interactions that the bacterium has
with the human host, ranging from asymptomatic nasopharyngeal colonisation affecting …

Global case-fatality rates in pediatric severe sepsis and septic shock: a systematic review and meta-analysis

B Tan, JJM Wong, R Sultana, JCJW Koh, M Jit… - JAMA …, 2019 - jamanetwork.com
Importance The global patterns and distribution of case-fatality rates (CFRs) in pediatric
severe sepsis and septic shock remain poorly described. Objective We performed a …

American College of Critical Care Medicine clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock

AL Davis, JA Carcillo, RK Aneja, AJ Deymann… - Critical care …, 2017 - journals.lww.com
Objectives: The American College of Critical Care Medicine provided 2002 and 2007
guidelines for hemodynamic support of newborn and pediatric septic shock. Provide the …

Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock: 2007 update from the American College of Critical Care Medicine

J Brierley, JA Carcillo, K Choong, T Cornell… - Critical care …, 2009 - journals.lww.com
Background: The Institute of Medicine calls for the use of clinical guidelines and practice
parameters to promote “best practices” and to improve patient outcomes. Objective: 2007 …

Brain natriuretic peptide: a marker of myocardial dysfunction and prognosis during severe sepsis

J Charpentier, CE Luyt, Y Fulla… - Critical care …, 2004 - journals.lww.com
Brain natriuretic peptide: A marker of myocardial dysfunctio... : Critical Care Medicine Brain
natriuretic peptide: A marker of myocardial dysfunction and prognosis during severe sepsis …

Cardiac troponin I predicts myocardial dysfunction and adverse outcome in septic shock

NJ Mehta, IA Khan, V Gupta, K Jani, RM Gowda… - International journal of …, 2004 - Elsevier
Objective: The objectives of this study were to determine myocardial injury in patients with
septic shock by measuring serum cardiac troponin I (cTnI), to evaluate relationship between …

Clinical significance of elevated troponin I levels in patients with nontraumatic subarachnoid hemorrhage

E Deibert, B Barzilai, AC Braverman, DF Edwards… - Journal of …, 2003 - thejns.org
Object. Aneurysmal subarachnoid hemorrhage (SAH) is associated with
electrocardiographic abnormalities, regional or focal wall-motion abnormalities on …

Bench-to-bedside review: significance and interpretation of elevated troponin in septic patients

R Favory, R Neviere - Critical care, 2006 - Springer
Because no bedside method is currently available to evaluate myocardial contractility
independent of loading conditions, a biological marker that could detect myocardial …

The role of cardiac troponin I as a prognosticator in critically ill medical patients: a prospective observational cohort study

DA King, S Codish, V Novack, L Barski, Y Almog - Critical Care, 2005 - Springer
Introduction Myocardial injury is frequently unrecognized in intensive care unit (ICU)
patients. Cardiac troponin I (cTnI), a surrogate of myocardial injury, has been shown to …