Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?

J Antonio, DG Candow, SC Forbes, B Gualano… - Journal of the …, 2021 - Springer
Supplementing with creatine is very popular amongst athletes and exercising individuals for
improving muscle mass, performance and recovery. Accumulating evidence also suggests …

International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine

RB Kreider, DS Kalman, J Antonio… - Journal of the …, 2017 - Taylor & Francis
Creatine is one of the most popular nutritional ergogenic aids for athletes. Studies have
consistently shown that creatine supplementation increases intramuscular creatine …

Creatine in health and disease

RB Kreider, JR Stout - Nutrients, 2021 - mdpi.com
Although creatine has been mostly studied as an ergogenic aid for exercise, training, and
sport, several health and potential therapeutic benefits have been reported. This is because …

Effects of creatine supplementation on brain function and health

SC Forbes, DM Cordingley, SM Cornish, B Gualano… - Nutrients, 2022 - mdpi.com
While the vast majority of research involving creatine supplementation has focused on
skeletal muscle, there is a small body of accumulating research that has focused on creatine …

Reactive oxygen species in skeletal muscle signaling

E Barbieri, P Sestili - Journal of signal transduction, 2012 - Wiley Online Library
Generation of reactive oxygen species (ROS) is a ubiquitous phenomenon in eukaryotic
cells′ life. Up to the 1990s of the past century, ROS have been solely considered as toxic …

[HTML][HTML] Mitochondrial creatine kinase in human health and disease

U Schlattner, M Tokarska-Schlattner… - Biochimica et Biophysica …, 2006 - Elsevier
Mitochondrial creatine kinase (MtCK), together with cytosolic creatine kinase isoenzymes
and the highly diffusible CK reaction product, phosphocreatine, provide a temporal and …

International Society of Sports Nutrition position stand: creatine supplementation and exercise

TW Buford, RB Kreider, JR Stout, M Greenwood… - Journal of the …, 2007 - Springer
Background Creatine has become one of the most extensively studied and scientifically
validated nutritional ergogenic aids for athletes. Additionally, creatine has been evaluated …

“Heads Up” for Creatine Supplementation and its Potential Applications for Brain Health and Function

DG Candow, SC Forbes, SM Ostojic, K Prokopidis… - Sports Medicine, 2023 - Springer
There is emerging interest regarding the potential beneficial effects of creatine
supplementation on indices of brain health and function. Creatine supplementation can …

Effectiveness of creatine supplementation on aging muscle and bone: focus on falls prevention and inflammation

DG Candow, SC Forbes, PD Chilibeck… - Journal of clinical …, 2019 - mdpi.com
Sarcopenia, defined as the age-related decrease in muscle mass, strength and physical
performance, is associated with reduced bone mass and elevated low-grade inflammation …

Creatine: endogenous metabolite, dietary, and therapeutic supplement

JT Brosnan, ME Brosnan - Annu. Rev. Nutr., 2007 - annualreviews.org
Creatine and phosphocreatine serve not only as an intracellular buffer for adenosine
triphosphate, but also as an energy shuttle for the movement of high-energy phosphates …