SM Mouneir, A Elhagrasi… - Egyptian Journal of …, 2022 - ejchem.journals.ekb.eg
Natural products chemistry has played a significant role in the advancement of physical and biological sciences and its interdisciplinary fields due to its unique applications and …
Abstract Sodium-glucose co-transporter 2 (SGLT-2) is a major transport protein responsible for reabsorption of glucose from the kidney back to the bloodstream. Inhibiting this protein …
The impact of next-generation biorecognition elements (ligands) will be determined by the ability to remotely control their binding activity for a target biomolecule in complex …
G Lanka, R Bathula, M Dasari, S Nakkala… - Journal of Receptors …, 2019 - Taylor & Francis
Type 2 diabetes mellitus is a metabolic disorder that requires potent therapeutic approaches. The FAM3B is a cytokine-like protein also referred to as PANcreatic-DERrived …
H Fei, C Zheng, X Liu, Q Li - Process Biochemistry, 2017 - Elsevier
Deoxy-d-ribose-5-phosphate aldolase (DERA) belongs to the family of lyases and can form C–C bonds to generate multiple chiral centers, thus providing an interesting route to …
Tuberculosis is one of the most life‐threatening acute infectious diseases diagnosed in humans. In the present investigation, a series of 16 new disubstituted 1, 3‐thiazetidines …
A Jadaun, N Subbarao, A Dixit - Journal of Photochemistry and …, 2017 - Elsevier
Cancer, the second major cause of mortality trailing the cardiovascular diseases, is a multifactorial heterogeneous disease and growing public health problem worldwide. Owing …
Natural products have been a great source of leads for cancer drug discovery. The cyclin- dependent kinases (CDKs) play a vital role in the initiation and progression of cancer. The …
P Ramesh, WH Shin, S Veerappapillai - Pharmaceutics, 2021 - mdpi.com
Rearranged during transfection (RET) is a tyrosine kinase oncogenic receptor, activated in several cancers including non-small-cell lung cancer (NSCLC). Multiple kinase inhibitors …