Striatal cholinergic interneurons (ChIs) are central for the processing and reinforcement of
reward‐related behaviors that are negatively affected in states of altered dopamine …

The striatum constitutes the main input structure of the basal ganglia and receives two major
excitatory glutamatergic inputs, from the cortex and the thalamus. Excitatory cortico‐and …

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is highly effective in
alleviating movement disability in patients with Parkinson's disease (PD). However, its …

The striatum is comprised of medium-sized spiny projection neurons (MSNs) and several
types of interneuron, and receives massive glutamatergic input from the cerebral cortex …

Key points• Fast spiking interneurons (FSIs) modulate output of the striatum and are
implicated in severe motor disorders.• Selective expression of the calcium‐binding protein …

The dorsal striatum, with its functional microcircuits galore, serves as the primary gateway of
the basal ganglia and is known to play a key role in implicit learning. Initially, excitatory …

Cholinergic interneurons have emerged as one of the key players controlling network
functions in the striatum. Extracellularly recorded cholinergic interneurons acquire …

Response to threatening environmental stimuli requires detection and encoding of important
environmental features that dictate threat. Aversive events are highly salient, which …

Striatal oscillatory activity is associated with movement, reward, and decision-making, and
observed in several interacting frequency bands. Local field potential recordings in rodent …

Long-term potentiation (LTP) of excitatory afferents to the dorsal striatum likely occurs with
learning to encode new skills and habits, yet corticostriatal LTP is challenging to evoke …