Fluorescence optical imaging in anticancer drug delivery

T Etrych, H Lucas, O Janoušková, P Chytil… - Journal of Controlled …, 2016 - Elsevier
In the past several decades, nanosized drug delivery systems with various targeting
functions and controlled drug release capabilities inside targeted tissues or cells have been …

Advances in optical imaging for pharmacological studies

A Arranz, J Ripoll - Frontiers in pharmacology, 2015 - frontiersin.org
Imaging approaches are an essential tool for following up over time representative
parameters of in vivo models, providing useful information in pharmacological studies. Main …

Recent technical advances in accelerating the clinical translation of small animal brain imaging: hybrid imaging, deep learning, and transcriptomics

W Ren, B Ji, Y Guan, L Cao, R Ni - Frontiers in Medicine, 2022 - frontiersin.org
Small animal models play a fundamental role in brain research by deepening the
understanding of the physiological functions and mechanisms underlying brain disorders …

Fluorescence imaging as a tool in preclinical evaluation of polymer-based nano-DDS systems intended for cancer treatment

T Etrych, O Janoušková, P Chytil - Pharmaceutics, 2019 - mdpi.com
Targeted drug delivery using nano-sized carrier systems with targeting functions to
malignant and inflammatory tissue and tailored controlled drug release inside targeted …

Atherosclerosis is associated with a decrease in cerebral microvascular blood flow and tissue oxygenation

B Li, X Lu, M Moeini, S Sakadžić, E Thorin, F Lesage - PLoS One, 2019 - journals.plos.org
Chronic atherosclerosis may cause cerebral hypoperfusion and inadequate brain
oxygenation, contributing to the progression of cognitive decline. In this study, we exploited …

Molecular imaging of vulnerable atherosclerotic plaques in animal models

S Gargiulo, M Gramanzini, M Mancini - International Journal of Molecular …, 2016 - mdpi.com
Atherosclerosis is characterized by intimal plaques of the arterial vessels that develop slowly
and, in some cases, may undergo spontaneous rupture with subsequent heart attack or …

An inversion scheme for hybrid fluorescence molecular tomography using a fuzzy inference system

P Mohajerani, V Ntziachristos - IEEE Transactions on medical …, 2015 - ieeexplore.ieee.org
The imaging performance of fluorescence molecular tomography (FMT) improves when
information from the underlying anatomy is incorporated into the inversion scheme, in the …

Bioluminescence tomography reconstruction in conjunction with an organ probability map as an anatomical reference

W Yin, X Li, Q Cao, H Wang, B Zhang - Biomedical Optics Express, 2022 - opg.optica.org
To alleviate the ill-posedness of bioluminescence tomography (BLT) reconstruction,
anatomical information from computed tomography (CT) or magnetic resonance imaging …

Three-way decision based reconstruction frame for fluorescence molecular tomography

H Yi, P Jiao, X Li, J Peng, X He - JOSA A, 2018 - opg.optica.org
Fluorescence molecular tomography (FMT) has been a promising imaging tool because it
allows an accurate localizaton and quantitative analysis of the fluorophore distribution in …

Bioluminescence tomography with structural information estimated via statistical mouse atlas registration

B Zhang, W Yin, H Liu, X Cao, H Wang - Biomedical optics express, 2018 - opg.optica.org
Due to an ill-posed and underestimated characteristic of bioluminescence tomography (BLT)
reconstruction, a priori anatomical information obtained from computed tomography (CT) or …