[HTML][HTML] Dosing extracellular vesicles

D Gupta, AM Zickler, S El Andaloussi - Advanced drug delivery reviews, 2021 - Elsevier
Extracellular vesicles (EVs) are natural nanoparticles containing biologically active
molecules. They are important mediators of intercellular communication and can be …

Cancer diagnosis: from tumor to liquid biopsy and beyond

R Vaidyanathan, RH Soon, P Zhang, K Jiang, CT Lim - Lab on a Chip, 2019 - pubs.rsc.org
Technological advancements in research on circulating biomarkers from patient derived
blood have enabled a less invasive means of diagnosing non-hematologic cancers …

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

Integrated SERS-vertical flow biosensor enabling multiplexed quantitative profiling of serological exosomal proteins in patients for accurate breast cancer subtyping

X Su, X Liu, Y Xie, M Chen, C Zheng, H Zhong, M Li - ACS nano, 2023 - ACS Publications
Protein profiles of exosomes (EXOs) in clinical samples of cancer patients have become a
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …

C Théry, KW Witwer, E Aikawa… - Journal of …, 2018 - Wiley Online Library
The last decade has seen a sharp increase in the number of scientific publications
describing physiological and pathological functions of extracellular vesicles (EVs), a …

Standardization of sample collection, isolation and analysis methods in extracellular vesicle research

KW Witwer, EI Buzás, LT Bemis, A Bora… - Journal of …, 2013 - Taylor & Francis
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles
(EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease …

[HTML][HTML] Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and …

E Van der Pol, FAW Coumans, AE Grootemaat… - Journal of Thrombosis …, 2014 - Elsevier
Background Enumeration of extracellular vesicles has clinical potential as a biomarker for
disease. In biological samples, the smallest and largest vesicles typically differ 25‐fold in …

Mesenchymal‐stem‐cell‐derived exosomes accelerate skeletal muscle regeneration

Y Nakamura, S Miyaki, H Ishitobi, S Matsuyama… - FEBS …, 2015 - Wiley Online Library
Mesenchymal stem cell (MSC) transplantation is used for treatment of many diseases. The
paracrine role of MSCs in tissue regeneration is attracting particular attention. We …

[HTML][HTML] Cancer-associated fibroblasts-derived exosomes suppress immune cell function in breast cancer via the miR-92/PD-L1 pathway

D Dou, X Ren, M Han, X Xu, X Ge, Y Gu… - Frontiers in …, 2020 - pmc.ncbi.nlm.nih.gov
Cancer-associated fibroblasts (CAFs) are an essential component in the tumor
microenvironment and have been reported to contribute to tumor progression through many …

Extracellular vesicles as drug delivery systems: lessons from the liposome field

R van der Meel, MHAM Fens, P Vader… - Journal of controlled …, 2014 - Elsevier
Extracellular vesicles (EVs) are membrane-derived particles surrounded by a (phospho)
lipid bilayer that are released by cells in the human body. In addition to direct cell-to-cell …