A comprehensive survey of recent advancements in molecular communication
With much advancement in the field of nanotechnology, bioengineering, and synthetic
biology over the past decade, microscales and nanoscales devices are becoming a reality …
biology over the past decade, microscales and nanoscales devices are becoming a reality …
Designing cell function: assembly of synthetic gene circuits for cell biology applications
M Xie, M Fussenegger - Nature Reviews Molecular Cell Biology, 2018 - nature.com
Synthetic biology is the discipline of engineering application-driven biological functionalities
that were not evolved by nature. Early breakthroughs of cell engineering, which were based …
that were not evolved by nature. Early breakthroughs of cell engineering, which were based …
Emerging biomedical applications of synthetic biology
W Weber, M Fussenegger - Nature Reviews Genetics, 2012 - nature.com
Synthetic biology aims to create functional devices, systems and organisms with novel and
useful functions on the basis of catalogued and standardized biological building blocks …
useful functions on the basis of catalogued and standardized biological building blocks …
Synthetic biology: integrated gene circuits
N Nandagopal, MB Elowitz - science, 2011 - science.org
A major goal of synthetic biology is to develop a deeper understanding of biological design
principles from the bottom up, by building circuits and studying their behavior in cells …
principles from the bottom up, by building circuits and studying their behavior in cells …
Systems biology of cellular rhythms
A Goldbeter, C Gérard, D Gonze, JC Leloup… - FEBS …, 2012 - Wiley Online Library
► Detailed survey of experimental and modeling approaches to cellular rhythms.► Cellular
rhythms in development: from cAMP oscillations to the segmentation clock.► Frequency …
rhythms in development: from cAMP oscillations to the segmentation clock.► Frequency …
p53 pulses diversify target gene expression dynamics in an mRNA half-life-dependent manner and delineate co-regulated target gene subnetworks
The transcription factor p53 responds to DNA double-strand breaks by increasing in
concentration in a series of pulses of fixed amplitude, duration, and period. How p53 pulses …
concentration in a series of pulses of fixed amplitude, duration, and period. How p53 pulses …
Synthetic switches and regulatory circuits in plants
J Andres, T Blomeier, MD Zurbriggen - Plant Physiology, 2019 - academic.oup.com
Synthetic biology is an established but ever-growing interdisciplinary field of research
currently revolutionizing biomedicine studies and the biotech industry. The engineering of …
currently revolutionizing biomedicine studies and the biotech industry. The engineering of …
Entrainment to periodic initiation and transition rates in a computational model for gene translation
Periodic oscillations play an important role in many biomedical systems. Proper functioning
of biological systems that respond to periodic signals requires the ability to synchronize with …
of biological systems that respond to periodic signals requires the ability to synchronize with …
Incoherent inputs enhance the robustness of biological oscillators
Robust biological oscillators retain the critical ability to function in the presence of
environmental perturbations. Although central architectures that support robust oscillations …
environmental perturbations. Although central architectures that support robust oscillations …
p53 pulse modulation differentially regulates target gene promoters to regulate cell fate decisions
MD Harton, WS Koh, AD Bunker, A Singh… - Molecular Systems …, 2019 - embopress.org
The p53 tumor suppressor regulates distinct responses to cellular stresses. Although
different stresses generate different p53 dynamics, the mechanisms by which cells decode …
different stresses generate different p53 dynamics, the mechanisms by which cells decode …