Therapeutic targeting of NF-κB in acute lung injury: a double-edged sword

MW Millar, F Fazal, A Rahman - Cells, 2022 - mdpi.com
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a devastating disease
that can be caused by a variety of conditions including pneumonia, sepsis, trauma, and most …

Recent advances in the molecular mechanisms underlying pyroptosis in sepsis

YL Gao, JH Zhai, YF Chai - Mediators of inflammation, 2018 - Wiley Online Library
Sepsis is recognized as a life‐threatening organ dysfunctional disease that is caused by
dysregulated host responses to infection. Up to now, sepsis still remains a dominant cause …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

[PDF][PDF] Guidelines for the use and interpretation of assays for monitoring autophagy

DJ Klionsky, K Abdelmohsen, MJ Abedin, A Abe - autophagy, 2016 - repository.upenn.edu
Many researchers, especially those new to the field, need to determine which criteria are
essential for demonstrating autophagy, either for the purposes of their own research, or in …

Differential regulation of autophagy and mitophagy in pulmonary diseases

S Aggarwal, P Mannam… - American Journal of …, 2016 - journals.physiology.org
Lysosomal-mediated degradation of intracellular lipids, proteins and organelles, known as
autophagy, represents a inducible adaptive response to lung injury resulting from exposure …

Mechanisms of TLR4-mediated autophagy and nitroxidative stress

K Zhang, Q Huang, S Deng, Y Yang, J Li… - Frontiers in Cellular and …, 2021 - frontiersin.org
Pathogenic infections have badly affected public health and the development of the
breeding industry. Billions of dollars are spent every year fighting against these pathogens …

Protective features of autophagy in pulmonary infection and inflammatory diseases

K Wang, Y Chen, P Zhang, P Lin, N Xie, M Wu - Cells, 2019 - mdpi.com
Autophagy is a highly conserved catabolic process involving autolysosomal degradation of
cellular components, including protein aggregates, damaged organelles (such as …

Role of Th17 cells, Treg cells, and Th17/Treg imbalance in immune homeostasis disorders in patients with chronic obstructive pulmonary disease

R Ma, H Su, K Jiao, J Liu - Immunity, Inflammation and Disease, 2023 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide, following strokes and cardiovascular diseases. Chronic lung inflammation is …

Autophagy, cell death, and cytokines in K. pneumoniae infection: therapeutic perspectives

S Wei, T Xu, Y Chen, K Zhou - Emerging Microbes & Infections, 2023 - Taylor & Francis
Klebsiella pneumoniae is a notorious nosocomial pathogen causing a wide range of
infections. The increasing trend of antimicrobial resistance obtained by the species …

Emerging biological functions of IL-17A: a new target in chronic obstructive pulmonary disease?

M Liu, K Wu, J Lin, Q Xie, Y Liu, Y Huang… - Frontiers in …, 2021 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease that
causes high rates of disability and mortality worldwide because of severe progressive and …