Sažetak Self-microemulsifying drug delivery system (SMEDDS) of lovastatin was aimed at
overcoming the problems of poor solubility and bioavailability. The formulation strategy …

Floating drug delivery system is a recent advancement in pharmaceutical technology which
has also several advantages over the conventional drug delivery systems. Those …

One of the complex processes in the human body is gastric emptying, as it is highly variable
which makes the in vivo performance of the drug delivery systems uncertain. To overcome …

Background Objective of this study is to show the potential use of natural gums in the
development of drug delivery systems. Therefore in this work gastro retentive tablet …

Lovastatin (LOV), an antihyperlipidimic agent, is characterized by low solubility/poor
dissolution and, thus, low bioavailability (< 5%). A beneficial effect on its bioavailability could …

Risperidone is effective in the treatment of positive as well as negative symptoms of
schizophrenia. But, there is a strong correlation between plasma levels of risperidone and its …

The use of polymers in different fields of modern medicine has generated significant
advances in tissue engineering, diagnostic and therapeutic strategies. Polymers have been …

Background A novel lovastatin (LVT)-loaded poly (lactic acid) microsphere suitable for oral
administration was developed in this study, and in vitro and in vivo characteristics were …

Felodipine (FD) has been widely used in anti-hypertensive treatment. However, it has
extremely low aqueous solubility and poor bioavailability. To address these problems, FD …

Scale-up of microspheres is major challenge at large scale manufacturing. The foremost
objective of this research was to study the impact of key process parameters and formulation …