Streptococcus pneumoniae (pneumococcus) kills nearly 1 million children annually, and the
emergence of antibiotic-resistant strains poses a serious threat to human health. Because …

Antibacterial drug discovery has experienced a paradigm shift from phenotypic screening for
antibacterial activity to rational inhibition of preselected targets. Functional genomics …

Previous studies have suggested that pneumococcal choline binding protein A (PcpA) is
important for the full virulence of Streptococcus pneumoniae, and its amino acid sequence …

Influenza A virus (IAV) is a major pathogen of the human respiratory tract, where the virus
coexists and interacts with bacterial populations comprising the respiratory tract microbiome …

Pefloxacin has been increasingly used in veterinary medicine to treat microbial infections.
To avoid using a labor-intensive instrumental method to detect the residue of pefloxacin in …

Optochin, a cinchona alkaloid derivative discovered over 100 years ago, possesses highly
selective antibacterial activity toward Streptococcus pneumoniae. Pneumococcal disease …

Streptococcus agalactiae (group B Streptococcus; GBS) remains a dominant cause of
serious neonatal infections. One aspect of GBS that renders it particularly virulent during the …

Among 2,882 Streptococcus pneumoniae sent to the Spanish Reference Laboratory during
2002, 75 (2.6%) were ciprofloxacin-resistant. Resistance was associated with older patients …

Streptococcus pyogenes is a human commensal and a bacterial pathogen responsible for a
wide variety of human diseases differing in symptoms, severity, and tissue tropism. The …

Chromosome segregation is an essential part of the bacterial cell cycle but is poorly
characterized in oval‐shaped streptococci. Using time‐lapse fluorescence microscopy and …