The nuclear receptor superfamily: A structural perspective

ER Weikum, X Liu, EA Ortlund - Protein Science, 2018 - Wiley Online Library
Nuclear receptors (NRs) are a family of transcription factors that regulate numerous
physiological processes such as metabolism, reproduction, inflammation, as well as the …

Sex and gender differences research design for basic, clinical, and population studies: essentials for investigators

JW Rich-Edwards, UB Kaiser, GL Chen… - Endocrine …, 2018 - academic.oup.com
A sex-and gender-informed perspective increases rigor, promotes discovery, and expands
the relevance of biomedical research. In the current era of accountability to present data for …

[HTML][HTML] Neurosteroids as regulators of neuroinflammation

C Yilmaz, K Karali, G Fodelianaki, A Gravanis… - Frontiers in …, 2019 - Elsevier
Neuroinflammation is a physiological protective response in the context of infection and
injury. However, neuroinflammation, especially if chronic, may also drive …

Progesterone and breast cancer

B Trabert, ME Sherman, N Kannan… - Endocrine …, 2020 - academic.oup.com
Synthetic progestogens (progestins) have been linked to increased breast cancer risk;
however, the role of endogenous progesterone in breast physiology and carcinogenesis is …

Revisiting the roles of progesterone and allopregnanolone in the nervous system: resurgence of the progesterone receptors

M Schumacher, C Mattern, A Ghoumari… - Progress in …, 2014 - Elsevier
Progesterone is commonly considered as a female reproductive hormone and is well-known
for its role in pregnancy. It is less well appreciated that progesterone and its metabolite …

[HTML][HTML] Tumor markers of breast cancer: New prospectives

AM Kabel - Journal of Oncological Sciences, 2017 - Elsevier
Tumor markers are substances produced by the tumors or by other cells of the body in
response to cancer or certain benign conditions. Although most of these markers are made …

Epigenetic dysregulation in endometriosis: implications for pathophysiology and therapeutics

RM Marquardt, DN Tran, BA Lessey… - Endocrine …, 2023 - academic.oup.com
Endometriosis is a prevalent gynecological condition associated with pelvic pain and
infertility. Despite more than a century of research, the etiology of endometriosis still eludes …

Premenstrual dysphoric disorder symptoms following ovarian suppression: triggered by change in ovarian steroid levels but not continuous stable levels

PJ Schmidt, PE Martinez, LK Nieman… - American Journal of …, 2017 - Am Psychiatric Assoc
Objective: Premenstrual dysphoric disorder (PMDD) symptoms are eliminated by ovarian
suppression and stimulated by administration of ovarian steroids, yet they appear with …

Oestrogen and progesterone action on endometrium: a translational approach to understanding endometrial receptivity

SL Young - Reproductive biomedicine online, 2013 - Elsevier
Embryo attachment and implantation is critical to successful reproduction of all eutherian
mammals, including humans; a better understanding of these processes could lead to …

Unraveling the Dynamics of Estrogen and Progesterone Signaling in the Endometrium: An Overview

ID Da Silva, V Wuidar, M Zielonka, C Pequeux - Cells, 2024 - pmc.ncbi.nlm.nih.gov
The endometrium is crucial for the perpetuation of human species. It is a complex and
dynamic tissue lining the inner wall of the uterus, regulated throughout a woman's life based …