MicroRNAs are short non-coding RNAs that are evolutionarily conserved and are pivotal
post-transcriptional mediators of gene regulation. Together with transcription factors and …

In the past decades, microRNAs (miRNA) have much attracted the attention of researchers
at the interface between life and theoretical sciences for their involvement in post …

Protein levels can be controlled by regulating protein synthesis or half life. The aim of this
paper is to investigate how introducing feedback in burst frequency or protein decay rate …

All vital functions of living cells rely on the production of various functional molecules
through gene expression. The production periods are burst-like and stochastic due to the …

Mechanistic models of stochastic gene expression are of considerable interest, but their
complexity often precludes tractable analytical expressions for messenger RNA (mRNA) and …

Regulatory molecules such as transcription factors are often present at relatively small copy
numbers in living cells. The copy number of a particular molecule fluctuates in time due to …

We study how sequestration mechanisms, such as protein binding to decoy sites and the
reversible formation of phase-separated condensates, alter the statistics of protein levels. To …

Noise is intrinsic to many important regulatory processes in living cells, and often forms
obstacles to be overcome for reliable biological functions. However, due to stochastic birth …

We study how sequestration mechanisms, such as protein binding to decoy sites and the
reversible formation of phaseseparated condensates, alter the statistics of protein levels. To …

Mechanistic models of stochastic gene expression are of considerable interest, but their
complexity often precludes tractable analytical expressions for mRNA and protein …