Non-alcoholic fatty liver disease: metabolic, genetic, epigenetic and environmental risk factors

O Juanola, S Martínez-López, R Francés… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent causes of chronic liver
disease in the Western world, probably due to the growing prevalence of obesity, metabolic …

Genetics and epigenetics of NAFLD and NASH: Clinical impact

M Eslam, L Valenti, S Romeo - Journal of hepatology, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is now recognised as the most common liver
disease worldwide. It encompasses a broad spectrum of conditions, from simple steatosis …

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

E Buzzetti, M Pinzani, EA Tsochatzis - Metabolism, 2016 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent and represents a growing
challenge in terms of prevention and treatment. Despite its high prevalence, only a small …

[HTML][HTML] Genetic and epigenetic factors determining NAFLD risk

W Jonas, A Schürmann - Molecular metabolism, 2021 - Elsevier
Background Hepatic steatosis is a common chronic liver disease that can progress into more
severe stages of NAFLD or promote the development of life-threatening secondary diseases …

DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery

M Ahrens, O Ammerpohl, W von Schönfels, J Kolarova… - Cell metabolism, 2013 - cell.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in
industrialized countries. Liver samples from morbidly obese patients (n= 45) with all stages …

Endocrine-disrupting chemicals and fatty liver disease

CE Foulds, LS Treviño, B York, CL Walker - Nature Reviews …, 2017 - nature.com
A growing epidemic of nonalcoholic fatty liver disease (NAFLD) is paralleling the increase in
the incidence of obesity and diabetes mellitus in countries that consume a Western diet. As …

In Vitro and in Vivo Models of Non-Alcoholic Fatty Liver Disease (NAFLD)

G Kanuri, I Bergheim - International journal of molecular sciences, 2013 - mdpi.com
By now, non-alcoholic fatty liver disease (NAFLD) is considered to be among the most
common liver diseases world-wide. NAFLD encompasses a broad spectrum of pathological …

Epigenetics in male reproduction: effect of paternal diet on sperm quality and offspring health

U Schagdarsurengin, K Steger - Nature Reviews Urology, 2016 - nature.com
Epigenetic inheritance and its underlying molecular mechanisms are among the most
intriguing areas of current biological and medical research. To date, studies have shown that …

Dietary factors, epigenetic modifications and obesity outcomes: progresses and perspectives

FI Milagro, ML Mansego, C De Miguel… - Molecular aspects of …, 2013 - Elsevier
Nutritional factors play a life-long role in human health. Indeed, there is growing evidence
that one of the mechanisms by which nutrients and bioactive compounds affect metabolic …

One-carbon metabolism and epigenetics

S Friso, S Udali, D De Santis, SW Choi - Molecular aspects of medicine, 2017 - Elsevier
The function of one-carbon metabolism is that of regulating the provision of methyl groups
for biological methylation reactions including that of DNA and histone proteins. Methylation …