Marine natural products

AR Carroll, BR Copp, RA Davis, RA Keyzers… - Natural Product …, 2020 - pubs.rsc.org
This review covers the literature published between January and December in 2018 for
marine natural products (MNPs), with 717 citations (706 for the period January to December …

Naturally Occurring Organohalogen Compounds—A Comprehensive Review

GW Gribble - Naturally Occurring Organohalogen Compounds, 2023 - Springer
The present volume is the third in a trilogy that documents naturally occurring
organohalogen compounds, bringing the total number—from fewer than 25 in 1968—to …

[图书][B] Naturally occurring organohalogen compounds

GW Gribble - 2023 - Springer
The previous two surveys documented a combined total of 4714 naturally occurring
organohalogen compounds, both biogenic and abiotic [1, 2]. In the subsequent two …

Ni-Catalysed intramolecular reductive aminocarbonylation of 2-haloaryl-tethered nitroarenes for the synthesis of dibenzazepine-based heterocycles

Z Feng, JA Ma, CW Cheung - Organic Chemistry Frontiers, 2022 - pubs.rsc.org
Herein, we describe an intramolecular reductive aminocarbonylation of haloaryl-tethered
nitroarenes with carbon monoxide to access dibenzazepine-based heterocycles. The use of …

Metabolic blockade-based genome mining reveals lipochain-linked dihydro-β-alanine synthetases involved in autucedine biosynthesis

H Zhang, C Zhang, Q Li, J Ma, J Ju - Organic Letters, 2022 - ACS Publications
Continuously mining the Streptomyces olivaceus SCSIO T05 genome leads to the
identification of new lipopeptides (autucedines A–C), constituting members of the 10th …

Comparative Genomics of Marine Sponge-Derived Streptomyces spp. Isolates SM17 and SM18 With Their Closest Terrestrial Relatives Provides Novel Insights Into …

EL Almeida, AF Carrillo Rincón, SA Jackson… - Frontiers in …, 2019 - frontiersin.org
The emergence of antibiotic resistant microorganisms has led to an increased need for the
discovery and development of novel antimicrobial compounds. Frequent rediscovery of the …

Genome Sequencing of Streptomyces olivaceus SCSIO T05 and Activated Production of Lobophorin CR4 via Metabolic Engineering and Genome Mining

C Zhang, W Ding, X Qin, J Ju - Marine drugs, 2019 - mdpi.com
Marine-sourced actinomycete genus Streptomyces continues to be an important source of
new natural products. Here we report the complete genome sequence of deep-sea-derived …

Chemistry, biosynthesis, and biological activity of halogenated compounds produced by marine microorganisms

J Wang, X Pang, C Chen, C Gao… - Chinese Journal of …, 2022 - Wiley Online Library
Comprehensive Summary Natural products derived from marine microorganisms have been
received great attention as a potential source of new compound entities for drug discovery …

Heterologous expression of the unusual terreazepine biosynthetic gene cluster reveals a promising approach for identifying new chemical scaffolds

LK Caesar, MT Robey, M Swyers, MN Islam, R Ye… - MBio, 2020 - Am Soc Microbiol
Advances in genome sequencing have revitalized natural product discovery efforts,
revealing the untapped biosynthetic potential of fungi. While the volume of genomic data …

Expanding the Chemical Diversity of Grisechelins via Heterologous Expression

W Liu, S Zhai, L Zhang, Y Chen, Z Liu… - Journal of Natural …, 2024 - ACS Publications
Thiazole scaffold-based small molecules exhibit a range of biological activities and play
important roles in drug discovery. Based on bioinformatics analysis, a putative biosynthetic …