Space travel presents a number of environmental challenges to the central nervous system,
including changes in gravitational acceleration that alter the terrestrial synergies between …

Brain metastases are the most common intracranial neoplasm and are seen in upwards of
10-30% of patients with cancer. For decades, whole brain radiation therapy (WBRT) was the …

Aim To evaluate the impact of ultra-rapid FLASH mouse whole brain irradiation on
hippocampal dendritic spines and neuroinflammation, factors associated with cognitive …

The Mars mission will result in an inevitable exposure to cosmic radiation that has been
shown to cause cognitive impairments in rodent models, and possibly in astronauts …

Cranial irradiation is used routinely for the treatment of nearly all brain tumors, but may lead
to progressive and debilitating impairments of cognitive function. Changes in synaptic …

Hippocampal-dependent cognitive functions rely on production of new neurons and
maintenance of dendritic structures to provide the synaptic plasticity needed for learning and …

Epidemiological studies on the atomic-bomb survivors, cancer survivors and occupational
cohorts provide strong evidence for multifaceted damage to brain after ionizing radiation …

Alzheimer's disease (AD) is the most common type of dementia. AD involves major
pathologies such as amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain. During …

Learning and memory deficits are early clinical manifestations of Huntington's disease (HD).
These cognitive impairments have been mainly associated with frontostriatal HD pathology; …

Cranial radiotherapy induces progressive and debilitating cognitive deficits, particularly in
long-term cancer survivors, which may in part be caused by the reduction of hippocampal …