Cough hypersensitivity and chronic cough

KF Chung, L McGarvey, WJ Song, AB Chang… - Nature Reviews …, 2022 - nature.com
Chronic cough is globally prevalent across all age groups. This disorder is challenging to
treat because many pulmonary and extrapulmonary conditions can present with chronic …

Internal senses of the vagus nerve

SL Prescott, SD Liberles - Neuron, 2022 - cell.com
The vagus nerve is an indispensable body-brain connection that controls vital aspects of
autonomic physiology like breathing, heart rate, blood pressure, and gut motility, reflexes …

The integrated brain network that controls respiration

F Krohn, M Novello, RS van der Giessen, CI De Zeeuw… - Elife, 2023 - elifesciences.org
Respiration is a brain function on which our lives essentially depend. Control of respiration
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …

Vagal afferent innervation of the airways in health and disease

SB Mazzone, BJ Undem - Physiological reviews, 2016 - journals.physiology.org
Vagal sensory neurons constitute the major afferent supply to the airways and lungs.
Subsets of afferents are defined by their embryological origin, molecular profile …

An airway-to-brain sensory pathway mediates influenza-induced sickness

NR Bin, SL Prescott, N Horio, Y Wang, IM Chiu… - Nature, 2023 - nature.com
Pathogen infection causes a stereotyped state of sickness that involves neuronally
orchestrated behavioural and physiological changes,. On infection, immune cells release a …

A student's guide to neural circuit tracing

C Saleeba, B Dempsey, S Le, A Goodchild… - Frontiers in …, 2019 - frontiersin.org
The mammalian nervous system is comprised of a seemingly infinitely complex network of
specialized synaptic connections that coordinate the flow of information through it. The field …

Neural correlates of cough hypersensitivity in humans: evidence for central sensitisation and dysfunctional inhibitory control

A Ando, D Smallwood, M McMahon, L Irving… - Thorax, 2016 - thorax.bmj.com
Introduction Chronic non-productive coughing is a major complication of pulmonary disease
and can also occur in many individuals without identifiable underlying pathology. The …

Identification of lung innervating sensory neurons and their target specificity

Y Su, J Barr, A Jaquish, J Xu… - American Journal of …, 2022 - journals.physiology.org
Known as the gas exchange organ, the lung is also critical for responding to the aerosol
environment in part through interaction with the nervous system. The diversity and specificity …

Local D2-to D1-neuron transmodulation updates goal-directed learning in the striatum

M Matamales, AE McGovern, JD Mi, SB Mazzone… - Science, 2020 - science.org
Extinction learning allows animals to withhold voluntary actions that are no longer related to
reward and so provides a major source of behavioral control. Although such learning is …

Nano-and neurotoxicology: An emerging discipline

A Bencsik, P Lestaevel, IG Canu - Progress in Neurobiology, 2018 - Elsevier
The present critical review analyzes the question of how nanoparticles from continuously
growing industrial production and use of nanomaterials may impact human brain health …