Can we engineer a human cardiac patch for therapy?

J Zhang, W Zhu, M Radisic… - Circulation …, 2018 - Am Heart Assoc
Some of the most significant leaps in the history of modern civilization—the development of
article in China, the steam engine, which led to the European industrial revolution, and the …

ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for …

R Madonna, LW Van Laake, HE Botker… - Cardiovascular …, 2019 - academic.oup.com
Morbidity and mortality from ischaemic heart disease (IHD) and heart failure (HF) remain
significant in Europe and are increasing worldwide. Patients with IHD or HF might benefit …

Progress in bioengineering strategies for heart regenerative medicine

T Häneke, M Sahara - International Journal of Molecular Sciences, 2022 - mdpi.com
The human heart has the least regenerative capabilities among tissues and organs, and
heart disease continues to be a leading cause of mortality in the industrialized world with …

Customizing the shape and microenvironment biochemistry of biocompatible macroscopic plant-derived cellulose scaffolds

RJ Hickey, DJ Modulevsky, CM Cuerrier… - … Science & Engineering, 2018 - ACS Publications
Plant-derived cellulose scaffolds constitute a highly viable and interesting biomaterial. They
retain a high flexibility in shape and structure, present the ability to tune surface …

Engineering human cardiac muscle patch constructs for prevention of post-infarction LV remodeling

L Wang, V Serpooshan, J Zhang - Frontiers in cardiovascular …, 2021 - frontiersin.org
Tissue engineering combines principles of engineering and biology to generate living tissue
equivalents for drug testing, disease modeling, and regenerative medicine. As techniques …

Photoacoustic Imaging of Embryonic Stem Cell‐Derived Cardiomyocytes in Living Hearts with Ultrasensitive Semiconducting Polymer Nanoparticles

X Qin, H Chen, H Yang, H Wu, X Zhao… - Advanced functional …, 2018 - Wiley Online Library
Human embryonic stem cell‐derived cardiomyocytes (hESC‐CMs) have become promising
tools to repair injured hearts. To achieve optimal outcomes, advanced molecular imaging …

Taking it personally: 3D bioprinting a patient-specific cardiac patch for the treatment of heart failure

N Matthews, B Pandolfo, D Moses, C Gentile - Bioengineering, 2022 - mdpi.com
Despite a massive global preventative effort, heart failure remains the major cause of death
globally. The number of patients requiring a heart transplant, the eventual last treatment …

Cardiac tissue engineering for the treatment of myocardial infarction

D Yu, X Wang, L Ye - Journal of Cardiovascular Development and …, 2021 - mdpi.com
Poor cell engraftment rate is one of the primary factors limiting the effectiveness of cell
transfer therapy for cardiac repair. Recent studies have shown that the combination of cell …

High-resolution imaging for the analysis and reconstruction of 3D microenvironments for regenerative medicine: An application-focused review

ME Klontzas, A Protonotarios - Bioengineering, 2021 - mdpi.com
The rapid evolution of regenerative medicine and its associated scientific fields, such as
tissue engineering, has provided great promise for multiple applications where replacement …

Imaging the cardiac extracellular matrix

MA Pinkert, RA Hortensius, BM Ogle… - … : Fundamental Science to …, 2018 - Springer
Cardiovascular disease is the global leading cause of death. One route to address this
problem is using biomedical imaging to measure the molecules and structures that surround …