Several studies suggest that variations in the concentration of plasma glycoproteins can
influence cellular changes in a large number of diseases. In recent years, proton nuclear …

This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

Protein glycosylation is one of the most significant post-translation modifications and plays a
critical role in various biological functions. Haptoglobin (Hp) is one of the acute-phase …

Serum haptoglobin (Hp), a highly sialylated biomolecule with four N‐glycosylation sites, is a
positive acute‐phase response glycoprotein that acts as an immunomodulator. Hp has …

A mass spectrometric method was developed to elucidate the N-glycan structures of serum
glycoproteins and utilize fucosylated glycans as potential markers for pancreatic cancer …

Occurrences of high values in patients with benign prostate disease and low values in
patients with highly suspicious cancer have diminished the trustworthiness of prostate …

Fucosylation is an important type of glycosylation involved in cancer, and fucosylated
proteins could be employed as cancer biomarkers. Previously, we reported that fucosylated …

Reversed-phase chromatographic separation of glycopeptides tends to be dominated by the
peptide composition. In contrast, capillary zone electrophoresis separation of glycopeptides …

A challenge in the treatment of lung cancer is the lack of early diagnostics. Here, we
describe the application of monoclonal antibody proteomics for discovery of a panel of …

Background Cholangiocarcinoma (CCA) is a silent tumor with a high mortality rate due to the
difficulty of early diagnosis and prediction of recurrence even after timely surgery. Serologic …