The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that is best
known for mediating the toxicity and tumour-promoting properties of the carcinogen 2, 3, 7, 8 …

The aryl hydrocarbon receptor (AhR) was initially identified as the receptor that binds and
mediates the toxic effects induced by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) and …

Abstract The European Commission asked EFSA for a scientific opinion on the risks for
animal and human health related to the presence of dioxins (PCDD/Fs) and DL‐PCBs in …

The aryl hydrocarbon receptor (AhR) is an important cytosolic, ligand-dependent
transcription factor. Emerging evidence suggests the promoting role of the AhR in the …

The aryl hydrocarbon receptor repressor (AhRR) was first described as a specific
competitive repressor of aryl hydrocarbon receptor (AhR) activity based on its ability to …

An adverse outcome pathway (AOP) describes the causal linkage between initial molecular
events and an adverse outcome at individual or population levels. Whilst there has been …

Dioxin and dioxin-like compounds are chlorinated organic pollutants formed during the
manufacturing of other chemicals. Dioxins are ligands of the aryl hydrocarbon receptor …

Ah receptor pathway intricacies; signaling through diverse protein partners and DNA-motifs -
Toxicology Research (RSC Publishing) DOI:10.1039/C4TX00236A Royal Society of …

The polyphenolic flavone chrysin has been evaluated as a natural chemopreventive agent
due to its anti-cancer effects in a variety of cancer cell lines. However, the mechanism of the …

The aryl hydrocarbon receptor (AhR) is known for mediating the toxicity of environmental
pollutants such as dioxins and numerous dioxin-like compounds, and is associated with the …